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Isaac Kohane
Isaac Kohane
Harvard Medical School, Children's Hospital, Brigham and Women's Hospital
Bestätigte E-Mail-Adresse bei hms.harvard.edu - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Cancer Genome Atlas Research Network Tissue source sites: Duke University ...
Nature 455 (7216), 1061-1068, 2008
74982008
Machine learning in medicine
A Rajkomar, J Dean, I Kohane
New England Journal of Medicine 380 (14), 1347-1358, 2019
28892019
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ...
Nature genetics 50 (5), 668-681, 2018
27012018
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
ME Patti, AJ Butte, S Crunkhorn, K Cusi, R Berria, S Kashyap, Y Miyazaki, ...
Proceedings of the national academy of sciences 100 (14), 8466-8471, 2003
24362003
Artificial intelligence in healthcare
KH Yu, AL Beam, IS Kohane
Nature biomedical engineering 2 (10), 719-731, 2018
22482018
Gene regulation and DNA damage in the ageing human brain
T Lu, Y Pan, SY Kao, C Li, I Kohane, J Chan, BA Yankner
Nature 429 (6994), 883-891, 2004
21802004
Big data and machine learning in health care
AL Beam, IS Kohane
Jama 319 (13), 1317-1318, 2018
17222018
Mutual information relevance networks: functional genomic clustering using pairwise entropy measurements
AJ Butte, IS Kohane
Biocomputing 2000, 418-429, 1999
14081999
Toward Precision Medicine: Building a Knowledge Network for Biomedical Research and a New Taxonomy of Disease
National Research Council
National Academies Press, 2011
1388*2011
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
SL Carter, AC Eklund, IS Kohane, LN Harris, Z Szallasi
Nature genetics 38 (9), 1043-1048, 2006
13172006
A mega-analysis of genome-wide association studies for major depressive disorder
Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium
Molecular psychiatry 18 (4), 2013
12672013
Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2)
SN Murphy, G Weber, M Mendis, V Gainer, HC Chueh, S Churchill, ...
Journal of the American Medical Informatics Association 17 (2), 124-130, 2010
10802010
Safety of the BNT162b2 mRNA Covid-19 vaccine in a nationwide setting
N Barda, N Dagan, Y Ben-Shlomo, E Kepten, J Waxman, R Ohana, ...
New England Journal of Medicine 385 (12), 1078-1090, 2021
10382021
Effectiveness of a third dose of the BNT162b2 mRNA COVID-19 vaccine for preventing severe outcomes in Israel: an observational study
N Barda, N Dagan, C Cohen, MA Hernán, M Lipsitch, IS Kohane, BY Reis, ...
The Lancet 398 (10316), 2093-2100, 2021
9332021
Adversarial attacks on medical machine learning
SG Finlayson, JD Bowers, J Ito, JL Zittrain, AL Beam, IS Kohane
Science 363 (6433), 1287-1289, 2019
9182019
Discovering statistically significant pathways in expression profiling studies
L Tian, SA Greenberg, SW Kong, J Altschuler, IS Kohane, PJ Park
Proceedings of the National Academy of Sciences 102 (38), 13544-13549, 2005
8342005
Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks
AJ Butte, P Tamayo, D Slonim, TR Golub, IS Kohane
Proceedings of the National Academy of Sciences 97 (22), 12182-12186, 2000
7942000
Genetic misdiagnoses and the potential for health disparities
AK Manrai, BH Funke, HL Rehm, MS Olesen, BA Maron, P Szolovits, ...
New England Journal of Medicine 375 (7), 655-665, 2016
7282016
SMART on FHIR: a standards-based, interoperable apps platform for electronic health records
JC Mandel, DA Kreda, KD Mandl, IS Kohane, RB Ramoni
Journal of the American Medical Informatics Association 23 (5), 899-908, 2016
7132016
Human disease classification in the postgenomic era: a complex systems approach to human pathobiology
J Loscalzo, I Kohane, AL Barabasi
Molecular systems biology 3 (1), 124, 2007
6952007
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