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Andrew Lutkewitte
Andrew Lutkewitte
Postdoctoral Research Fellow, Washington University
Bestätigte E-Mail-Adresse bei wustl.edu
Titel
Zitiert von
Zitiert von
Jahr
Regulation of signaling and metabolism by lipin-mediated phosphatidic acid phosphohydrolase activity
AJ Lutkewitte, BN Finck
Biomolecules 10 (10), 1386, 2020
522020
Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids
MR Martino, M Gutiérrez-Aguilar, NKH Yiew, AJ Lutkewitte, JM Singer, ...
Cell reports 39 (4), 2022
422022
Mitochondrial pyruvate carrier inhibition initiates metabolic crosstalk to stimulate branched chain amino acid catabolism
D Ferguson, SJ Eichler, NKH Yiew, JR Colca, K Cho, GJ Patti, TM Shew, ...
Molecular metabolism 70, 101694, 2023
352023
Lipin deactivation after acetaminophen overdose causes phosphatidic acid accumulation in liver and plasma in mice and humans and enhances liver regeneration
AJ Lutkewitte, GG Schweitzer, S Kennon-McGill, MM Clemens, LP James, ...
Food and Chemical Toxicology 115, 273-283, 2018
312018
Monoacylglycerol acyltransferase 1 knockdown exacerbates hepatic ischemia/reperfusion injury in mice with hepatic steatosis
KHH Liss, SE Ek, AJ Lutkewitte, TA Pietka, M He, P Skaria, E Tycksen, ...
Liver Transplantation 27 (1), 116-133, 2021
182021
Hepatic monoacylglycerol acyltransferase 1 is induced by prolonged food deprivation to modulate the hepatic fasting response [S]
AJ Lutkewitte, KS McCommis, GG Schweitzer, KT Chambers, MJ Graham, ...
Journal of lipid research 60 (3), 528-538, 2019
162019
Multiple antisense oligonucleotides targeted against monoacylglycerol acyltransferase 1 (Mogat1) improve glucose metabolism independently of Mogat1
AJ Lutkewitte, JM Singer, TM Shew, MR Martino, AM Hall, M He, BN Finck
Molecular Metabolism 49, 101204, 2021
112021
Mitochondrial Pyruvate Carrier Inhibition Attenuates Hepatic Stellate Cell Activation and Liver Injury in a Mouse Model of Metabolic Dysfunction-associated Steatotic Liver Disease
M Habibi, D Ferguson, SJ Eichler, MM Chan, A LaPoint, TM Shew, M He, ...
bioRxiv, 2023
8*2023
Mitochondrial pyruvate carrier inhibition initiates metabolic crosstalk to stimulate branched chain amino acid catabolism. Mol Metab. 2023; 70: 101694
D Ferguson, SJ Eichler, NKH Yiew, JR Colca, K Cho, GJ Patti, TM Shew, ...
DOI: https://doi. org/10.1016/j. molmet, 101694, 2023
52023
Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and gluconeogenesis in mice
NKH Yiew, S Deja, D Ferguson, K Cho, C Jarasvaraparn, M Jacome-Sosa, ...
Iscience 26 (11), 2023
42023
Monoacylglycerol O‐acyltransferase 1 lowers adipocyte differentiation capacity in vitro but does not affect adiposity in mice
JM Singer, TM Shew, D Ferguson, MK Renkemeyer, TA Pietka, AM Hall, ...
Obesity 30 (11), 2122-2133, 2022
42022
VCD-induced menopause mouse model reveals reprogramming of hepatic metabolism
R Kumari, ME Ponte, E Franczak, JC Prom, MF O'Neil, ME Sardiu, ...
Molecular Metabolism 82, 101908, 2024
32024
Ube4A maintains metabolic homeostasis and facilitates insulin signaling in vivo
S Mukherjee, M Chakraborty, EN Msengi, J Haubner, J Zhang, ...
Molecular Metabolism 75, 101767, 2023
32023
Adipocyte lipin 1 is positively associated with metabolic health in humans and regulates systemic metabolism in mice
A LaPoint, JM Singer, D Ferguson, TM Shew, MK Renkemeyer, ...
bioRxiv, 2023.02. 01.526676, 2023
32023
Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and glycerol-mediated gluconeogenesis in mice
NKH Yiew, S Deja, D Ferguson, K Cho, C Jarasvaraparn, M Jacome-Sosa, ...
bioRxiv, 2023
22023
Dynamic changes in the mouse hepatic lipidome following warm ischemia reperfusion injury
KHH Liss, M Mousa, S Bucha, A Lutkewitte, J Allegood, LA Cowart, ...
Scientific reports 14 (1), 3584, 2024
12024
1575-P: Glycerol Metabolism and Gluconeogenesis in Mice Lacking the Mitochondrial Pyruvate Carrier in Hepatocytes
N YIEW, D FERGUSON, K CHO, S DEJA, C JARASVARAPARN, X FU, ...
Diabetes 72 (Supplement_1), 2023
12023
Glucolipotoxic Stress-Induced Mig6 Desensitizes EGFR Signaling and Promotes Pancreatic Beta Cell Death
YC Chen, AJ Lutkewitte, HD Basavarajappa, PT Fueger
Metabolites 13 (5), 627, 2023
12023
Regulation of PGC1α downstream of the insulin signaling pathway plays a role in the hepatic proteotoxicity of mutant α1-antitrypsin deficiency variant Z
DA Rudnick, J Huang, T Hidvegi, AS Chu, P Hale, A Munanairi, ...
Gastroenterology 163 (1), 270-284, 2022
12022
Monoacylglycerol O-acyltransferase 1 is required for adipocyte differentiation in vitro but does not affect adiposity in mice
JM Singer, TM Shew, D Ferguson, MK Renkemeyer, TA Pietka, AM Hall, ...
bioRxiv, 2022.02. 14.480414, 2022
12022
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