Sodium butyrate improves memory function in an Alzheimer's disease mouse model when administered at an advanced stage of disease progression N Govindarajan, RC Agis-Balboa, J Walter, F Sananbenesi, A Fischer Journal of Alzheimer's Disease 26 (1), 187-197, 2011 | 419 | 2011 |
Derivation of human midbrain-specific organoids from neuroepithelial stem cells AS Monzel, LM Smits, K Hemmer, S Hachi, EL Moreno, T van Wuellen, ... Stem cell reports 8 (5), 1144-1154, 2017 | 403 | 2017 |
Distinct antimicrobial peptide expression determines host species-specific bacterial associations S Franzenburg, J Walter, S Künzel, J Wang, JF Baines, TCG Bosch, ... Proceedings of the National Academy of Sciences 110 (39), E3730-E3738, 2013 | 344 | 2013 |
Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release T Narita, S Ito, Y Higashijima, WK Chu, K Neumann, J Walter, S Satpathy, ... Molecular Cell 81 (10), 2166-2182. e6, 2021 | 131 | 2021 |
3D cultures of Parkinson's disease‐specific dopaminergic neurons for high content phenotyping and drug testing S Bolognin, M Fossépré, X Qing, J Jarazo, J Ščančar, EL Moreno, ... Advanced Science 6 (1), 1800927, 2019 | 126 | 2019 |
FACS-assisted CRISPR-Cas9 genome editing facilitates Parkinson's disease modeling J Arias-Fuenzalida, J Jarazo, X Qing, J Walter, G Gomez-Giro, SL Nickels, ... Stem Cell Reports 9 (5), 1423-1431, 2017 | 103 | 2017 |
Neural stem cells of Parkinson's disease patients exhibit aberrant mitochondrial morphology and functionality J Walter, S Bolognin, PMA Antony, SL Nickels, SK Poovathingal, ... Stem cell reports 12 (5), 878-889, 2019 | 93 | 2019 |
CRISPR/Cas9 and piggyBac-mediated footprint-free LRRK2-G2019S knock-in reveals neuronal complexity phenotypes and α-Synuclein modulation in dopaminergic neurons X Qing, J Walter, J Jarazo, J Arias-Fuenzalida, AL Hillje, JC Schwamborn Stem Cell Research 24, 44-50, 2017 | 75 | 2017 |
Parkinson's disease phenotypes in patient neuronal cultures and brain organoids improved by 2‐Hydroxypropyl‐β‐Cyclodextrin treatment J Jarazo, K Barmpa, J Modamio, C Saraiva, S Sabaté‐Soler, I Rosety, ... Movement Disorders 37 (1), 80-94, 2022 | 54 | 2022 |
Impaired mitochondrial–endoplasmic reticulum interaction and mitophagy in Miro1-mutant neurons in Parkinson’s disease C Berenguer-Escuder, D Grossmann, P Antony, G Arena, K Wasner, ... Human molecular genetics 29 (8), 1353-1364, 2020 | 44 | 2020 |
The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1 J Walter, S Bolognin, SK Poovathingal, S Magni, D Gerard, PMA Antony, ... Cell Reports 37 (3), 2021 | 31 | 2021 |
Acetylation of histone H2B marks active enhancers and predicts CBP/p300 target genes T Narita, Y Higashijima, S Kilic, T Liebner, J Walter, C Choudhary Nature Genetics 55 (4), 679-692, 2023 | 26 | 2023 |
Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients SL Nickels, J Walter, S Bolognin, D Gérard, C Jaeger, X Qing, J Tisserand, ... Parkinsonism & Related Disorders 67, 48-55, 2019 | 20 | 2019 |
Automated high-throughput high-content autophagy and mitophagy analysis platform J Arias-Fuenzalida, J Jarazo, J Walter, G Gomez-Giro, JI Forster, ... Scientific Reports 9 (1), 9455, 2019 | 17 | 2019 |
Parkinson’s disease phenotypes in patient specific brain organoids are improved by HP-β-CD treatment J Jarazo, K Barmpa, I Rosety, LM Smits, J Arias-Fuenzalida, J Walter, ... BioRxiv, 813089, 2019 | 12 | 2019 |
A unique H2B acetylation signature marks active enhancers and predicts their target genes T Narita, Y Higashijima, S Kilic, T Liebner, J Walter, C Choudhary bioRxiv, 2022.07. 18.500459, 2022 | 7 | 2022 |
Acetylation of histones and non-histone proteins is not a mere consequence of ongoing transcription T Liebner, S Kilic, J Walter, H Aibara, T Narita, C Choudhary Nature Communications 15 (1), 4962, 2024 | 2 | 2024 |
Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson’s disease patients carrying the heterozygous mutations c. 815G> A … A Chemla, G Arena, G Onal, J Walter, C Berenguer-Escuder, ... Stem Cell Research 71, 103145, 2023 | 2 | 2023 |
2-hydroxypropyl-beta-cyclodextrin for use in a method of treatment of a parkinsonian condition J Jarazo, J Walter, J Schwamborn WO Patent WO2019219741A1, 2019 | 2 | 2019 |
Human induced pluripotent stem cell-derived neuronal progenitors are a suitable and effective drug discovery model for neurological mtDNA disorders J Walter, SL Nickels, JC Schwamborn Stem Cell Investigation 4, 2017 | 1 | 2017 |