Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation C Fang, Z Wang, C Han, SL Safgren, KA Helmin, ER Adelman, V Serafin, ... Genome biology 21, 1-30, 2020 | 95 | 2020 |
Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127 S Montoya, J Bourcier, M Noviski, H Lu, MC Thompson, A Chirino, J Jahn, ... Science 383 (6682), eadi5798, 2024 | 59 | 2024 |
Hepatic interferon regulatory factor 6 alleviates liver steatosis and metabolic disorder by transcriptionally suppressing peroxisome proliferator‐activated receptor γ in mice J Tong, CJ Han, JZ Zhang, WZ He, GJ Zhao, XU Cheng, L Zhang, ... Hepatology 69 (6), 2471-2488, 2019 | 56 | 2019 |
Modulation of RNA splicing enhances response to BCL2 inhibition in leukemia E Wang, JMB Pineda, WJ Kim, S Chen, J Bourcier, M Stahl, SJ Hogg, ... Cancer Cell 41 (1), 164-180. e8, 2023 | 53 | 2023 |
Posttranslational regulation of the exon skipping machinery controls aberrant splicing in leukemia Y Zhou, C Han, E Wang, AH Lorch, V Serafin, BK Cho, BT Gutierrez Diaz, ... Cancer discovery 10 (9), 1388-1409, 2020 | 52 | 2020 |
ANP32A regulates histone H3 acetylation and promotes leukemogenesis X Yang, B Lu, X Sun, C Han, C Fu, K Xu, M Wang, D Li, Z Chen, P Opal, ... Leukemia 32 (7), 1587-1597, 2018 | 43 | 2018 |
Induction of INKIT by viral infection negatively regulates antiviral responses through inhibiting phosphorylation of p65 and IRF3 B Lu, Y Ren, X Sun, C Han, H Wang, Y Chen, Q Peng, Y Cheng, X Cheng, ... Cell host & microbe 22 (1), 86-98. e4, 2017 | 40 | 2017 |
SF3B1 homeostasis is critical for survival and therapeutic response in T cell leukemia C Han, A Khodadadi-Jamayran, AH Lorch, Q Jin, V Serafin, P Zhu, ... Science Advances 8 (3), eabj8357, 2022 | 29 | 2022 |
Metabolic injury of hepatocytes promotes progression of NAFLD and AALD R Carvalho-Gontijo, C Han, L Zhang, V Zhang, M Hosseini, K Mekeel, ... Seminars in liver disease 42 (03), 233-249, 2022 | 19 | 2022 |
ANP32A dysregulation contributes to abnormal megakaryopoiesis in acute megakaryoblastic leukemia X Sun, B Lu, C Han, W Qiu, Q Jin, D Li, Q Li, Q Yang, Q Wen, P Opal, ... Blood cancer journal 7 (12), 661, 2017 | 13 | 2017 |
Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia Q Jin, B Gutierrez Diaz, T Pieters, Y Zhou, S Narang, I Fijalkwoski, C Borin, ... Science Advances 8 (49), eabq8437, 2022 | 10 | 2022 |
Non-genetic mechanisms of drug resistance in acute leukemias A Calderon, C Han, S Karma, E Wang Trends in Cancer 10 (1), 38-51, 2024 | 6 | 2024 |
Multi-modal analysis of human hepatic stellate cells identifies novel therapeutic targets for metabolic dysfunction-associated steatotic liver disease HY Kim, SB Rosenthal, X Liu, C Miciano, X Hou, M Miller, J Buchanan, ... Journal of Hepatology, 2024 | 2 | 2024 |
Multispecies transcriptomics identifies SIKE as a MAPK repressor that prevents NASH progression L Bai, W Qu, X Cheng, H Yang, YP Huang, Z Wang, C Han, RF Tian, F Hu, ... Science Translational Medicine 16 (734), eade7347, 2024 | 1 | 2024 |
T-ALL and the talented Mr IL7Rα C Han, P Ntziachristos Blood, The Journal of the American Society of Hematology 138 (12), 1003-1004, 2021 | 1 | 2021 |
LARP6 regulates the mRNA translation of fibrogenic genes in liver fibrosis HY Kim, O Mizrahi, W Lee, SB Rosenthal, C Han, BA Yee, SM Blue, ... bioRxiv, 2025.01. 16.633226, 2025 | | 2025 |
LARP6 REGULATES TRANSLATION OF COLLAGEN TYPE I/III MRNAS IN ACTIVATED HEPATIC STELLATE CELLS (HSCS) FROM PATIENT LIVERS WITH MASH AND METALD HY Kim, O Mizrahi, W Lee, SB Rosenthal, C Han, B Yee, S Blue, J Diaz, ... HEPATOLOGY 80, S1556-S1557, 2024 | | 2024 |
Aberrant 3'UTR processing regulates a tumor suppressor network in AML E Wang, C Han, A Calderon, A Lawal, SH Rajendran, S Karma, ... Cancer Research 84 (6_Supplement), 5628-5628, 2024 | | 2024 |
Dysregulated RNA splicing promotes AML quiescence and chemoresistance E Wang, C Han, A Calderon, A Lawal, N Hariramani, E Crosse, R Bradley Cancer Research 84 (6_Supplement), 5851-5851, 2024 | | 2024 |
Aberrant 3'UTR Processing Regulates Leukemogenesis and Therapy Resistance E Wang, C Han, A Calderon Blood 142 (Supplement 1), 5760-5760, 2023 | | 2023 |