Murat Iskar
Murat Iskar
FMI, Switzerland
Bestätigte E-Mail-Adresse bei
Zitiert von
Zitiert von
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines
A Ori, N Banterle, M Iskar, A Andrés-Pons, C Escher, HK Bui, L Sparks, ...
Molecular Systems Biology 9 (1), 2013
The landscape of viral associations in human cancers
M Zapatka*, I Borozan*, DS Brewer*, M Iskar*, A Grundhoff, M Alawi, ...
Nature Genetics, 1-12, 2020
IL4I1 is a metabolic immune checkpoint that activates the AHR and promotes tumor progression
A Sadik, LFS Patterson, S Öztürk, SR Mohapatra, V Panitz, PF Secker, ...
Cell 182 (5), 1252-1270. e34, 2020
Tumor-derived exosomes modulate PD-L1 expression in monocytes
F Haderk, R Schulz, M Iskar, LL Cid, T Worst, KV Willmund, A Schulz, ...
Science immunology 2 (13), eaah5509, 2017
Prediction of drug combinations by integrating molecular and pharmacological data
XM Zhao, M Iskar, G Zeller, M Kuhn, V Van Noort, P Bork
PLoS computational biology 7 (12), e1002323, 2011
Integrated transcriptome and proteome analyses reveal organ-specific proteome deterioration in old rats
A Ori, BH Toyama, MS Harris, T Bock, M Iskar, P Bork, NT Ingolia, ...
Cell systems 1 (3), 224-237, 2015
Drug-induced regulation of target expression
M Iskar, M Campillos, M Kuhn, LJ Jensen, V van Noort, P Bork
PLoS computational biology 6 (9), e1000925, 2010
Luminal signalling links cell communication to tissue architecture during organogenesis
S Durdu, M Iskar, C Revenu, N Schieber, A Kunze, P Bork, Y Schwab, ...
Nature 515 (7525), 120-124, 2014
Characterization of drug‐induced transcriptional modules: towards drug repositioning and functional understanding
M Iskar, G Zeller, P Blattmann, M Campillos, M Kuhn, KH Kaminska, ...
Molecular systems biology 9 (1), 662, 2013
Drug discovery in the age of systems biology: the rise of computational approaches for data integration
M Iskar*, G Zeller*, XM Zhao, V van Noort, P Bork
Current opinion in biotechnology 23 (4), 609-616, 2012
Network neighbors of drug targets contribute to drug side-effect similarity
L Brouwers, M Iskar, G Zeller, V Van Noort, P Bork
PloS one 6 (7), e22187, 2011
Spatiotemporal variation of mammalian protein complex stoichiometries
A Ori*, M Iskar*, K Buczak, P Kastritis, L Parca, A Andrés-Pons, S Singer, ...
Genome biology 17 (1), 1, 2016
Novel drug candidates for the treatment of metastatic colorectal cancer through global inverse gene-expression profiling
V van Noort*, S Schölch*, M Iskar*, G Zeller, K Ostertag, C Schweitzer, ...
Cancer research 74 (20), 5690-5699, 2014
Identification and analyses of extra-cranial and cranial rhabdoid tumor molecular subgroups reveal tumors with cytotoxic T cell infiltration
HJE Chun, PD Johann, K Milne, M Zapatka, A Buellesbach, N Ishaque, ...
Cell reports 29 (8), 2338-2354. e7, 2019
DvD: An R/Cytoscape pipeline for drug repurposing using public repositories of gene expression data
C Pacini, F Iorio, E Goncalves, M Iskar, T Klabunde, P Bork, ...
Bioinformatics 29 (1), 132-134, 2013
Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity
BS Hanna, L Llao-Cid, M Iskar, PM Roessner, LC Klett, JKL Wong, Y Paul, ...
Immunity 54 (12), 2825-2841. e10, 2021
Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations
E Pfaff, C Aichmüller, M Sill, D Stichel, M Snuderl, MA Karajannis, ...
Acta neuropathologica 139, 243-257, 2020
Quantitative proteome landscape of the NCI-60 cancer cell lines
T Guo, A Luna, VN Rajapakse, CC Koh, Z Wu, W Liu, Y Sun, H Gao, ...
Iscience 21, 664-680, 2019
The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR
S Scharaw, M Iskar, A Ori, G Boncompain, V Laketa, I Poser, E Lundberg, ...
Journal of Cell Biology 215 (4), 543-558, 2016
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