| BRCA1 RING function is essential for tumor suppression but dispensable for therapy resistance R Drost, P Bouwman, S Rottenberg, U Boon, E Schut, S Klarenbeek, ... Cancer cell 20 (6), 797-809, 2011 | 300 | 2011 |
| Modeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland S Annunziato, SM Kas, M Nethe, H Yücel, J Del Bravo, C Pritchard, RB Ali, ... Genes & development 30 (12), 1470-1480, 2016 | 166 | 2016 |
| BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1 R Drost, KK Dhillon, H Van Der Gulden, I Van Der Heijden, I Brandsma, ... The Journal of clinical investigation 126 (8), 2903-2918, 2016 | 134 | 2016 |
| XenofilteR: computational deconvolution of mouse and human reads in tumor xenograft sequence data RJC Kluin, K Kemper, T Kuilman, JR de Ruiter, V Iyer, JV Forment, ... BMC bioinformatics 19, 1-15, 2018 | 123 | 2018 |
| Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma SM Kas, JR De Ruiter, K Schipper, S Annunziato, E Schut, S Klarenbeek, ... Nature genetics 49 (8), 1219-1230, 2017 | 92 | 2017 |
| Multiple low dose therapy as an effective strategy to treat EGFR inhibitor-resistant NSCLC tumours JM Fernandes Neto, E Nadal, E Bosdriesz, SN Ooft, L Farre, C McLean, ... Nature communications 11 (1), 3157, 2020 | 82 | 2020 |
| A preclinical mouse model of invasive lobular breast cancer metastasis CW Doornebal, S Klarenbeek, TM Braumuller, CN Klijn, M Ciampricotti, ... Cancer research 73 (1), 353-363, 2013 | 81 | 2013 |
| Loss of p120-catenin induces metastatic progression of breast cancer by inducing anoikis resistance and augmenting growth factor receptor signaling RCJ Schackmann, S Klarenbeek, EJ Vlug, S Stelloo, M Van Amersfoort, ... Cancer research 73 (15), 4937-4949, 2013 | 65 | 2013 |
| PTEN loss in E-cadherin-deficient mouse mammary epithelial cells rescues apoptosis and results in development of classical invasive lobular carcinoma MC Boelens, M Nethe, S Klarenbeek, JR de Ruiter, E Schut, N Bonzanni, ... Cell reports 16 (8), 2087-2101, 2016 | 63 | 2016 |
| Truncated FGFR2 is a clinically actionable oncogene in multiple cancers D Zingg, J Bhin, J Yemelyanenko, SM Kas, F Rolfs, C Lutz, JK Lee, ... Nature 608 (7923), 609-617, 2022 | 62 | 2022 |
| Cross-species comparison of aCGH data from mouse and human BRCA1- and BRCA2-mutated breast cancers H Holstege, E van Beers, A Velds, X Liu, SA Joosse, S Klarenbeek, ... BMC cancer 10, 1-16, 2010 | 49 | 2010 |
| Effect of growth-promoting 17β-estradiol, 19-nortestosterone and dexamethasone on circulating levels of nine potential biomarker candidates in veal calves G Cacciatore, SWF Eisenberg, C Situ, MH Mooney, P Delahaut, ... Analytica Chimica Acta 637 (1-2), 351-359, 2009 | 47 | 2009 |
| Transcriptomics and transposon mutagenesis identify multiple mechanisms of resistance to the FGFR inhibitor AZD4547 SM Kas, JR De Ruiter, K Schipper, E Schut, L Bombardelli, E Wientjens, ... Cancer Research 78 (19), 5668-5679, 2018 | 42 | 2018 |
| Genetically engineered mouse models of PI3K signaling in breast cancer S Klarenbeek, MH van Miltenburg, J Jonkers Molecular Oncology 7 (2), 146-164, 2013 | 40 | 2013 |
| CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer JM Houthuijzen, R De Bruijn, E Van Der Burg, AP Drenth, E Wientjens, ... Nature Communications 14 (1), 183, 2023 | 37 | 2023 |
| Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L‐dose dependency in HDAC1‐deficient thymic lymphoma H Vlaming, CM McLean, T Korthout, MF Alemdehy, S Hendriks, C Lancini, ... The EMBO Journal 38 (14), e101564, 2019 | 35 | 2019 |
| RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells Z Zhang, X Kong, MA Ligtenberg, SE Van Hal-van Veen, NL Visser, ... Cell Reports Medicine 3 (6), 2022 | 31 | 2022 |
| Somatic structural rearrangements in genetically engineered mouse mammary tumors I Varela, C Klijn, PJ Stephens, LJ Mudie, L Stebbings, D Galappaththige, ... Genome biology 11, 1-12, 2010 | 28 | 2010 |
| Expression of receptors for luteinizing hormone, gastric-inhibitory polypeptide, and vasopressin in normal adrenal glands and cortisol-secreting adrenocortical tumors in dogs S Galac, VJ Kars, S Klarenbeek, KJ Teerds, JA Mol, HS Kooistra Domestic animal endocrinology 39 (1), 63-75, 2010 | 23 | 2010 |
| Influence of 17β-oestradiol, nortestosterone and dexamethasone on the adaptive immune response in veal calves SWF Eisenberg, G Cacciatore, S Klarenbeek, AA Bergwerff, AP Koets Research in veterinary science 84 (2), 199-205, 2008 | 20 | 2008 |
