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S. Nik-Zainal
S. Nik-Zainal
Bestätigte E-Mail-Adresse bei cam.ac.uk
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Signatures of mutational processes in human cancer
LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ...
nature 500 (7463), 415-421, 2013
103852013
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
PJ Stephens, CD Greenman, B Fu, F Yang, GR Bignell, LJ Mudie, ...
cell 144 (1), 27-40, 2011
26912011
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
S Nik-Zainal, H Davies, J Staaf, M Ramakrishna, D Glodzik, X Zou, ...
Nature 534 (7605), 47-54, 2016
23232016
Mutational processes molding the genomes of 21 breast cancers
S Nik-Zainal, LB Alexandrov, DC Wedge, P Van Loo, CD Greenman, ...
Cell 149 (5), 979-993, 2012
21492012
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
1971*2020
The landscape of cancer genes and mutational processes in breast cancer
PJ Stephens, PS Tarpey, H Davies, P Van Loo, C Greenman, DC Wedge, ...
Nature 486 (7403), 400-404, 2012
19482012
The life history of 21 breast cancers
S Nik-Zainal, P Van Loo, DC Wedge, LB Alexandrov, CD Greenman, ...
Cell 149 (5), 994-1007, 2012
16102012
The patterns and dynamics of genomic instability in metastatic pancreatic cancer
PJ Campbell, S Yachida, LJ Mudie, PJ Stephens, ED Pleasance, ...
Nature 467 (7319), 1109-1113, 2010
15882010
Somatic SF3B1 Mutation in Myelodysplasia with Ring Sideroblasts
E Papaemmanuil, M Cazzola, J Boultwood, L Malcovati, P Vyas, D Bowen, ...
New England Journal of Medicine 365 (15), 1384-1395, 2011
14762011
Deciphering signatures of mutational processes operative in human cancer
LB Alexandrov, S Nik-Zainal, DC Wedge, PJ Campbell, MR Stratton
Cell reports 3 (1), 246-259, 2013
13372013
A small-cell lung cancer genome with complex signatures of tobacco exposure
ED Pleasance, PJ Stephens, S O’Meara, DJ McBride, A Meynert, D Jones, ...
Nature 463 (7278), 184-190, 2010
13132010
Mutational signatures associated with tobacco smoking in human cancer
LB Alexandrov, YS Ju, K Haase, P Van Loo, I Martincorena, S Nik-Zainal, ...
Science 354 (6312), 618-622, 2016
11192016
Clock-like mutational processes in human somatic cells
LB Alexandrov, PH Jones, DC Wedge, JE Sale, PJ Campbell, ...
Nature genetics 47 (12), 1402-1407, 2015
10632015
HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures
H Davies, D Glodzik, S Morganella, LR Yates, J Staaf, X Zou, ...
Nature medicine 23 (4), 517-525, 2017
10242017
Heterogeneity of genomic evolution and mutational profiles in multiple myeloma
N Bolli, H Avet-Loiseau, DC Wedge, P Van Loo, LB Alexandrov, ...
Nature communications 5 (1), 2997, 2014
10132014
Mechanisms underlying mutational signatures in human cancers
T Helleday, S Eshtad, S Nik-Zainal
Nature reviews genetics 15 (9), 585-598, 2014
9812014
Subclonal diversification of primary breast cancer revealed by multiregion sequencing
LR Yates, M Gerstung, S Knappskog, C Desmedt, G Gundem, P Van Loo, ...
Nature medicine 21 (7), 751-759, 2015
8632015
Recurrent rearrangements of chromosome 1q21. 1 and variable pediatric phenotypes
HC Mefford, AJ Sharp, C Baker, A Itsara, Z Jiang, K Buysse, S Huang, ...
New England Journal of Medicine 359 (16), 1685-1699, 2008
8592008
Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone
S Behjati, PS Tarpey, N Presneau, S Scheipl, N Pillay, P Van Loo, ...
Nature genetics 45 (12), 1479-1482, 2013
8422013
A compendium of mutational signatures of environmental agents
JE Kucab, X Zou, S Morganella, M Joel, AS Nanda, E Nagy, C Gomez, ...
Cell 177 (4), 821-836. e16, 2019
5812019
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