Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation JV Lee, A Carrer, S Shah, NW Snyder, S Wei, S Venneti, AJ Worth, ... Cell metabolism 20 (2), 306-319, 2014 | 581 | 2014 |
Single-cell transcriptomics of the human endocrine pancreas YJ Wang, J Schug, KJ Won, C Liu, A Naji, D Avrahami, ML Golson, ... Diabetes 65 (10), 3028-3038, 2016 | 408 | 2016 |
AMPK–SKP2–CARM1 signalling cascade in transcriptional regulation of autophagy HJR Shin, H Kim, S Oh, JG Lee, M Kee, HJ Ko, MN Kweon, KJ Won, ... Nature 534 (7608), 553-557, 2016 | 407 | 2016 |
Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice MJ Harms, J Ishibashi, W Wang, HW Lim, S Goyama, T Sato, M Kurokawa, ... Cell metabolism 19 (4), 593-604, 2014 | 398 | 2014 |
EBF2 determines and maintains brown adipocyte identity S Rajakumari, J Wu, J Ishibashi, HW Lim, AH Giang, KJ Won, RR Reed, ... Cell metabolism 17 (4), 562-574, 2013 | 396 | 2013 |
Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue DA Hill, HW Lim, YH Kim, WY Ho, YH Foong, VL Nelson, HCB Nguyen, ... Proceedings of the National Academy of Sciences 115 (22), E5096-E5105, 2018 | 382 | 2018 |
Epigenetic regulation of the DLK1-MEG3 microRNA cluster in human type 2 diabetic islets V Kameswaran, NC Bramswig, LB McKenna, M Penn, J Schug, NJ Hand, ... Cell metabolism 19 (1), 135-145, 2014 | 376 | 2014 |
ChatGPT and large language models in academia: opportunities and challenges JG Meyer, RJ Urbanowicz, PCN Martin, K O’Connor, R Li, PC Peng, ... BioData Mining 16 (1), 20, 2023 | 359 | 2023 |
Dynamic chromatin remodeling mediated by polycomb proteins orchestrates pancreatic differentiation of human embryonic stem cells R Xie, LJ Everett, HW Lim, NA Patel, J Schug, E Kroon, OG Kelly, A Wang, ... Cell stem cell 12 (2), 224-237, 2013 | 265 | 2013 |
Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor Z Sun, D Feng, B Fang, SE Mullican, SH You, HW Lim, LJ Everett, ... Molecular cell 52 (6), 769-782, 2013 | 261 | 2013 |
Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis T Alenghat, LC Osborne, SA Saenz, D Kobuley, CGK Ziegler, SE Mullican, ... Nature 504 (7478), 153-157, 2013 | 253 | 2013 |
Ebf2 is a selective marker of brown and beige adipogenic precursor cells W Wang, M Kissig, S Rajakumari, L Huang, H Lim, KJ Won, P Seale Proceedings of the National Academy of Sciences 111 (40), 14466-14471, 2014 | 241 | 2014 |
Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo SH You, HW Lim, Z Sun, M Broache, KJ Won, MA Lazar Nature structural & molecular biology 20 (2), 182-187, 2013 | 226 | 2013 |
An iPSC line from human pancreatic ductal adenocarcinoma undergoes early to invasive stages of pancreatic cancer progression J Kim, JP Hoffman, RK Alpaugh, AD Rhim, M Reichert, BZ Stanger, ... Cell reports 3 (6), 2088-2099, 2013 | 209 | 2013 |
Rev-erbα dynamically modulates chromatin looping to control circadian gene transcription YH Kim, SA Marhon, Y Zhang, DJ Steger, KJ Won, MA Lazar Science 359 (6381), 1274-1277, 2018 | 198 | 2018 |
A PRDM16-driven metabolic signal from adipocytes regulates precursor cell fate W Wang, J Ishibashi, S Trefely, M Shao, AJ Cowan, A Sakers, HW Lim, ... Cell metabolism 30 (1), 174-189. e5, 2019 | 191 | 2019 |
Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge MJ Emmett, HW Lim, J Jager, HJ Richter, M Adlanmerini, LC Peed, ... Nature 546 (7659), 544-548, 2017 | 184 | 2017 |
Genomic redistribution of GR monomers and dimers mediates transcriptional response to exogenous glucocorticoid in vivo HW Lim, NH Uhlenhaut, A Rauch, J Weiner, S Hübner, N Hübner, KJ Won, ... Genome research 25 (6), 836-844, 2015 | 184 | 2015 |
PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program MJ Harms, HW Lim, Y Ho, SN Shapira, J Ishibashi, S Rajakumari, ... Genes & development 29 (3), 298-307, 2015 | 150 | 2015 |
Metazoan nuclear pores provide a scaffold for poised genes and mediate induced enhancer-promoter contacts P Pascual-Garcia, B Debo, JR Aleman, JA Talamas, Y Lan, NH Nguyen, ... Molecular cell 66 (1), 63-76. e6, 2017 | 143 | 2017 |