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Marcello Allegretti
Marcello Allegretti
Dompé Farmaceutici spa
Bestätigte E-Mail-Adresse bei dompe.com
Titel
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Zitiert von
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CXCR1 and CXCR2 chemokine receptor agonists produced by tumors induce neutrophil extracellular traps that interfere with immune cytotoxicity
Á Teijeira, S Garasa, M Gato, C Alfaro, I Migueliz, A Cirella, C de Andrea, ...
Immunity 52 (5), 856-871. e8, 2020
4672020
Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury
R Bertini, M Allegretti, C Bizzarri, A Moriconi, M Locati, G Zampella, ...
Proceedings of the National Academy of Sciences 101 (32), 11791-11796, 2004
3792004
Tumor-produced interleukin-8 attracts human myeloid-derived suppressor cells and elicits extrusion of neutrophil extracellular traps (NETs)
C Alfaro, A Teijeira, C Oñate, G Perez, MF Sanmamed, MP Andueza, ...
Clinical Cancer Research 22 (15), 3924-3936, 2016
3622016
ELR+ CXC chemokines and their receptors (CXC chemokine receptor 1 and CXC chemokine receptor 2) as new therapeutic targets
C Bizzarri, AR Beccari, R Bertini, MR Cavicchia, S Giorgini, M Allegretti
Pharmacology & therapeutics 112 (1), 139-149, 2006
2702006
Phase II randomized, double-masked, vehicle-controlled trial of recombinant human nerve growth factor for neurotrophic keratitis
S Bonini, A Lambiase, P Rama, F Sinigaglia, M Allegretti, W Chao, ...
Ophthalmology 125 (9), 1332-1343, 2018
247*2018
Topical recombinant human nerve growth factor (cenegermin) for neurotrophic keratopathy: a multicenter randomized vehicle-controlled pivotal trial
SC Pflugfelder, M Massaro-Giordano, VL Perez, P Hamrah, SX Deng, ...
Ophthalmology 127 (1), 14-26, 2020
1942020
CXCR1/2 inhibition enhances pancreatic islet survival after transplantation
A Citro, E Cantarelli, P Maffi, R Nano, R Melzi, A Mercalli, E Dugnani, ...
The Journal of clinical investigation 122 (10), 3647-3651, 2012
1722012
LANCL2 is necessary for abscisic acid binding and signaling in human granulocytes and in rat insulinoma cells
L Sturla, C Fresia, L Guida, S Bruzzone, S Scarfì, C Usai, F Fruscione, ...
Journal of Biological Chemistry 284 (41), 28045-28057, 2009
1582009
Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice
A Zarbock, M Allegretti, K Ley
British journal of pharmacology 155 (3), 357-364, 2008
1442008
2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors
M Allegretti, R Bertini, MC Cesta, C Bizzarri, R Di Bitondo, V Di Cioccio, ...
Journal of medicinal chemistry 48 (13), 4312-4331, 2005
1422005
Repertaxin, a novel inhibitor of rat CXCR2 function, inhibits inflammatory responses that follow intestinal ischaemia and reperfusion injury
DG Souza, R Bertini, AT Vieira, FQ Cunha, S Poole, M Allegretti, F Colotta, ...
British journal of pharmacology 143 (1), 132-142, 2004
1252004
Treatment with DF 2162, a non‐competitive allosteric inhibitor of CXCR1/2, diminishes neutrophil influx and inflammatory hypernociception in mice
TM Cunha, MM Barsante, AT Guerrero, WA Verri Jr, SH Ferreira, ...
British journal of pharmacology 154 (2), 460-470, 2008
1122008
Design of noncompetitive interleukin-8 inhibitors acting on CXCR1 and CXCR2
A Moriconi, MC Cesta, MN Cervellera, A Aramini, S Coniglio, S Colagioia, ...
Journal of medicinal chemistry 50 (17), 3984-4002, 2007
1112007
Targeting C5a: recent advances in drug discovery
M Allegretti, A Moriconi, AR Beccari, RD Bitondo, C Bizzarri, R Bertini, ...
Current medicinal chemistry 12 (2), 217-236, 2005
1042005
Blockade of the chemokine receptor CXCR2 ameliorates adjuvant‐induced arthritis in rats
MM Barsante, TM Cunha, M Allegretti, F Cattani, F Policani, C Bizzarri, ...
British journal of pharmacology 153 (5), 992-1002, 2008
962008
CXCR1/2 inhibition blocks and reverses type 1 diabetes in mice
A Citro, A Valle, E Cantarelli, A Mercalli, S Pellegrini, D Liberati, ...
Diabetes 64 (4), 1329-1340, 2015
902015
The role of interleukin-8 in lung inflammation and injury: implications for the management of COVID-19 and hyperinflammatory acute respiratory distress syndrome
MC Cesta, M Zippoli, C Marsiglia, EM Gavioli, F Mantelli, M Allegretti, ...
Frontiers in pharmacology 12, 808797, 2022
842022
Chemokine signaling in chemotherapy-induced neuropathic pain
L Brandolini, M d’Angelo, A Antonosante, A Cimini, M Allegretti
International journal of molecular sciences 20 (12), 2904, 2019
832019
Targeting the minor pocket of C5aR for the rational design of an oral allosteric inhibitor for inflammatory and neuropathic pain relief
A Moriconi, TM Cunha, GR Souza, AH Lopes, FQ Cunha, VL Carneiro, ...
Proceedings of the National Academy of Sciences 111 (47), 16937-16942, 2014
782014
Targeting CXCR1 on breast cancer stem cells: signaling pathways and clinical application modelling
L Brandolini, L Cristiano, A Fidoamore, M De Pizzol, E Di Giacomo, ...
Oncotarget 6 (41), 43375, 2015
772015
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