Steven MC Chan
Steven MC Chan
Princess Margaret Cancer Centre
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Zitiert von
Zitiert von
Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution
MR Corces, JD Buenrostro, B Wu, PG Greenside, SM Chan, JL Koenig, ...
Nature genetics 48 (10), 1193-1203, 2016
Isocitrate dehydrogenase 1 and 2 mutations induce BCL-2 dependence in acute myeloid leukemia
SM Chan, D Thomas, MR Corces-Zimmerman, S Xavy, S Rastogi, ...
Nature medicine 21 (2), 178-184, 2015
Circulating tumor DNA and liquid biopsy in oncology
DW Cescon, SV Bratman, SM Chan, LL Siu
Nature cancer 1 (3), 276-290, 2020
Isocitrate dehydrogenase mutations in myeloid malignancies
BC Medeiros, AT Fathi, CD DiNardo, DA Pollyea, SM Chan, R Swords
Leukemia 31 (2), 272-281, 2017
Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia
SM Chan, AP Weng, R Tibshirani, JC Aster, PJ Utz
Blood, The Journal of the American Society of Hematology 110 (1), 278-286, 2007
Proteome-wide analysis in Saccharomyces cerevisiae identifies several PHD fingers as novel direct and selective binding modules of histone H3 methylated at either lysine 4 or …
X Shi, I Kachirskaia, KL Walter, JHA Kuo, A Lake, F Davrazou, SM Chan, ...
Journal of Biological Chemistry 282 (4), 2450-2455, 2007
Selective tyrosine kinase inhibition by imatinib mesylate for the treatment of autoimmune arthritis
RT Paniagua, O Sharpe, PP Ho, SM Chan, A Chang, JP Higgins, ...
The Journal of clinical investigation 116 (10), 2633-2642, 2006
Protein microarrays for multiplex analysis of signal transduction pathways
SM Chan, J Ermann, L Su, CG Fathman, PJ Utz
Nature medicine 10 (12), 1390-1396, 2004
Biological and clinical consequences of NPM1 mutations in AML
EM Heath, SM Chan, MD Minden, T Murphy, LI Shlush, AD Schimmer
Leukemia 31 (4), 798-807, 2017
Leukemia-associated cohesin mutants dominantly enforce stem cell programs and impair human hematopoietic progenitor differentiation
C Mazumdar, Y Shen, S Xavy, F Zhao, A Reinisch, R Li, MR Corces, ...
Cell stem cell 17 (6), 675-688, 2015
Role of antigen-presenting cells in mediating tolerance and autoimmunity
KM Garza, SM Chan, R Suri, LT Nguyen, B Odermatt, SP Schoenberger, ...
The Journal of Experimental Medicine 191 (11), 2021-2028, 2000
Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes
P Matre, J Velez, R Jacamo, Y Qi, X Su, T Cai, SM Chan, A Lodi, ...
Oncotarget 7 (48), 79722, 2016
Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response
D Sharon, S Cathelin, S Mirali, JM Di Trani, DJ Yanofsky, KA Keon, ...
Science translational medicine 11 (516), eaax2863, 2019
Multiplexed protein array platforms for analysis of autoimmune diseases
I Balboni, SM Chan, M Kattah, JD Tenenbaum, AJ Butte, PJ Utz
Annu. Rev. Immunol. 24 (1), 391-418, 2006
Role of DNMT3A, TET2, and IDH1/2 mutations in pre-leukemic stem cells in acute myeloid leukemia
SM Chan, R Majeti
International journal of hematology 98, 648-657, 2013
Superenhancer analysis defines novel epigenomic subtypes of non-APL AML, including an RARα dependency targetable by SY-1425, a potent and selective RARα agonist
MR McKeown, MR Corces, ML Eaton, C Fiore, E Lee, JT Lopez, ...
Cancer discovery 7 (10), 1136-1153, 2017
An array of possibilities for the study of autoimmunity
CG Fathman, L Soares, SM Chan, PJ Utz
Nature 435 (7042), 605-611, 2005
Murine CD4+ CD25+ regulatory T cells fail to undergo chromatin remodeling across the proximal promoter region of the IL-2 gene
L Su, RJ Creusot, EM Gallo, SM Chan, PJ Utz, CG Fathman, J Ermann
The Journal of Immunology 173 (8), 4994-5001, 2004
Relapse-fated latent diagnosis subclones in acute B lineage leukemia are drug tolerant and possess distinct metabolic programs
SM Dobson, L García-Prat, RJ Vanner, J Wintersinger, E Waanders, Z Gu, ...
Cancer discovery 10 (4), 568-587, 2020
Systematic discovery of mutation-specific synthetic lethals by mining pan-cancer human primary tumor data
S Sinha, D Thomas, S Chan, Y Gao, D Brunen, D Torabi, A Reinisch, ...
Nature communications 8 (1), 15580, 2017
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