| Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes RJ Perry, JPG Camporez, R Kursawe, PM Titchenell, D Zhang, CJ Perry, ... Cell 160 (4), 745-758, 2015 | 746 | 2015 |
| Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate S Zhao, C Jang, J Liu, K Uehara, M Gilbert, L Izzo, X Zeng, S Trefely, ... Nature 579 (7800), 586-591, 2020 | 428 | 2020 |
| Unraveling the regulation of hepatic metabolism by insulin PM Titchenell, MA Lazar, MJ Birnbaum Trends in Endocrinology & Metabolism 28 (7), 497-505, 2017 | 427 | 2017 |
| Direct hepatocyte insulin signaling is required for lipogenesis but is dispensable for the suppression of glucose production PM Titchenell, WJ Quinn, M Lu, Q Chu, W Lu, C Li, H Chen, BR Monks, ... Cell metabolism 23 (6), 1154-1166, 2016 | 299 | 2016 |
| Resolving the paradox of hepatic insulin resistance D Santoleri, PM Titchenell Cellular and molecular gastroenterology and hepatology 7 (2), 447-456, 2019 | 288 | 2019 |
| Hepatic insulin signalling is dispensable for suppression of glucose output by insulin in vivo PM Titchenell, Q Chu, BR Monks, MJ Birnbaum Nature communications 6 (1), 7078, 2015 | 185 | 2015 |
| The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver K Patel, M Foretz, A Marion, DG Campbell, R Gourlay, N Boudaba, ... Nature communications 5 (1), 4535, 2014 | 183 | 2014 |
| The role of skeletal muscle Akt in the regulation of muscle mass and glucose homeostasis N Jaiswal, MG Gavin, WJ Quinn Iii, TS Luongo, RG Gelfer, JA Baur, ... Molecular metabolism 28, 1-13, 2019 | 161 | 2019 |
| Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1 BS Gosis, S Wada, C Thorsheim, K Li, S Jung, JH Rhoades, Y Yang, ... Science 376 (6590), eabf8271, 2022 | 88 | 2022 |
| mTORC1 stimulates phosphatidylcholine synthesis to promote triglyceride secretion WJ Quinn, M Wan, SV Shewale, R Gelfer, DJ Rader, MJ Birnbaum, ... The Journal of clinical investigation 127 (11), 4207-4215, 2017 | 87 | 2017 |
| SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeeding H Jang, GY Lee, CP Selby, G Lee, YG Jeon, JH Lee, KKY Cheng, ... Nature communications 7 (1), 12180, 2016 | 87 | 2016 |
| Novel atypical PKC inhibitors prevent vascular endothelial growth factor-induced blood–retinal barrier dysfunction PM Titchenell, CM Lin, JM Keil, JM Sundstrom, CD Smith, DA Antonetti Biochemical Journal 446 (3), 455-467, 2012 | 82 | 2012 |
| Physiological suppression of lipotoxic liver damage by complementary actions of HDAC3 and SCAP/SREBP R Papazyan, Z Sun, YH Kim, PM Titchenell, DA Hill, W Lu, M Damle, ... Cell metabolism 24 (6), 863-874, 2016 | 80 | 2016 |
| Using the past to inform the future: anti-VEGF therapy as a road map to develop novel therapies for diabetic retinopathy PM Titchenell, DA Antonetti Diabetes 62 (6), 1808-1815, 2013 | 76 | 2013 |
| Early B cell factor activity controls developmental and adaptive thermogenic gene programming in adipocytes AR Angueira, SN Shapira, J Ishibashi, S Sampat, J Sostre-Colón, ... Cell reports 30 (9), 2869-2878. e4, 2020 | 53 | 2020 |
| AKT controls protein synthesis and oxidative metabolism via combined mTORC1 and FOXO1 signalling to govern muscle physiology N Jaiswal, M Gavin, E Loro, J Sostre‐Colón, PA Roberson, K Uehara, ... Journal of cachexia, sarcopenia and muscle 13 (1), 495-514, 2022 | 46 | 2022 |
| Shared PPARα/γ target genes regulate brown adipocyte thermogenic function Y Shen, Y Su, FJ Silva, AH Weller, J Sostre-Colón, PM Titchenell, ... Cell Reports 30 (9), 3079-3091. e5, 2020 | 43 | 2020 |
| MondoA drives muscle lipid accumulation and insulin resistance B Ahn, S Wan, N Jaiswal, RB Vega, DE Ayer, PM Titchenell, X Han, ... JCI insight 4 (15), 2019 | 33 | 2019 |
| Insulin regulation of hepatic lipid homeostasis K Uehara, D Santoleri, AEG Whitlock, PM Titchenell Comprehensive Physiology 13 (3), 4785, 2023 | 26 | 2023 |
| Inhibition of atypical protein kinase C reduces inflammation-induced retinal vascular permeability C Lin, PM Titchenell, JM Keil, A Garcia-Ocaña, MT Bolinger, SF Abcouwer, ... The American journal of pathology 188 (10), 2392-2405, 2018 | 26 | 2018 |
