| Reprogramming human T cell function and specificity with non-viral genome targeting TL Roth, C Puig-Saus, R Yu, E Shifrut, J Carnevale, PJ Li, J Hiatt, J Saco, ... Nature 559 (7714), 405-409, 2018 | 807 | 2018 |
| Pervasive functional translation of noncanonical human open reading frames J Chen, AD Brunner, JZ Cogan, JK Nuñez, AP Fields, B Adamson, ... Science 367 (6482), 1140-1146, 2020 | 502 | 2020 |
| Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing JK Nuñez, J Chen, GC Pommier, JZ Cogan, JM Replogle, C Adriaens, ... Cell 184 (9), 2503-2519. e17, 2021 | 451 | 2021 |
| Versatile protein tagging in cells with split fluorescent protein D Kamiyama, S Sekine, B Barsi-Rhyne, J Hu, B Chen, LA Gilbert, ... Nature communications 7 (1), 11046, 2016 | 434 | 2016 |
| Structure of the human BK channel Ca2+-activation apparatus at 3.0 Å resolution P Yuan, MD Leonetti, AR Pico, Y Hsiung, R MacKinnon Science 329 (5988), 182-186, 2010 | 357 | 2010 |
| OpenCell: Endogenous tagging for the cartography of human cellular organization NH Cho, KC Cheveralls, AD Brunner, K Kim, AC Michaelis, P Raghavan, ... Science 375 (6585), eabi6983, 2022 | 260 | 2022 |
| A scalable strategy for high-throughput GFP tagging of endogenous human proteins MD Leonetti, S Sekine, D Kamiyama, JS Weissman, B Huang Proceedings of the National Academy of Sciences 113 (25), E3501-E3508, 2016 | 240 | 2016 |
| Improved split fluorescent proteins for endogenous protein labeling S Feng, S Sekine, V Pessino, H Li, MD Leonetti, B Huang Nature communications 8 (1), 370, 2017 | 237 | 2017 |
| Functional and structural analysis of the human SLO3 pH-and voltage-gated K+ channel MD Leonetti, P Yuan, Y Hsiung, R MacKinnon Proceedings of the National Academy of Sciences 109 (47), 19274-19279, 2012 | 177 | 2012 |
| Open structure of the Ca2+ gating ring in the high-conductance Ca2+-activated K+ channel P Yuan, MD Leonetti, Y Hsiung, R MacKinnon Nature 481 (7379), 94-97, 2012 | 163 | 2012 |
| Ion selectivity in a semisynthetic K+ channel locked in the conductive conformation FI Valiyaveetil, M Leonetti, TW Muir, R MacKinnon Science 314 (5801), 1004-1007, 2006 | 163 | 2006 |
| Epi-illumination SPIM for volumetric imaging with high spatial-temporal resolution B Yang, X Chen, Y Wang, S Feng, V Pessino, N Stuurman, NH Cho, ... Nature methods 16 (6), 501-504, 2019 | 149 | 2019 |
| Spatiotemporal dissection of the cell cycle with single-cell proteogenomics D Mahdessian, AJ Cesnik, C Gnann, F Danielsson, L Stenström, M Arif, ... Nature 590 (7847), 649-654, 2021 | 144 | 2021 |
| Mapping the nucleolar proteome reveals a spatiotemporal organization related to intrinsic protein disorder L Stenström, D Mahdessian, C Gnann, AJ Cesnik, W Ouyang, ... Molecular systems biology 16 (8), e9469, 2020 | 137 | 2020 |
| Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation JJ Chen, DL Nathaniel, P Raghavan, M Nelson, R Tian, E Tse, JY Hong, ... Journal of Biological Chemistry 294 (50), 18952-18966, 2019 | 123 | 2019 |
| Large dataset enables prediction of repair after CRISPR–Cas9 editing in primary T cells RT Leenay, A Aghazadeh, J Hiatt, D Tse, TL Roth, R Apathy, E Shifrut, ... Nature biotechnology 37 (9), 1034-1037, 2019 | 114 | 2019 |
| Self-supervised deep learning encodes high-resolution features of protein subcellular localization H Kobayashi, KC Cheveralls, MD Leonetti, LA Royer Nature methods 19 (8), 995-1003, 2022 | 83 | 2022 |
| Structural basis of NR2B-selective antagonist recognition by N-methyl-D-aspartate receptors L Mony, L Krzaczkowski, M Leonetti, A Le Goff, K Alarcon, J Neyton, ... Molecular pharmacology 75 (1), 60-74, 2009 | 69 | 2009 |
| Conserved functions of ether lipids and sphingolipids in the early secretory pathway N Jiménez-Rojo, MD Leonetti, V Zoni, A Colom, S Feng, NR Iyengar, ... Current Biology 30 (19), 3775-3787. e7, 2020 | 67 | 2020 |
| Revealing architectural order with quantitative label-free imaging and deep learning SM Guo, LH Yeh, J Folkesson, IE Ivanov, AP Krishnan, MG Keefe, ... Elife 9, e55502, 2020 | 65 | 2020 |
