Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma J Zhao, AX Chen, RD Gartrell, AM Silverman, L Aparicio, T Chu, ... Nature medicine 25 (3), 462-469, 2019 | 738 | 2019 |
New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis Y Hou, J Zhao, W Martin, A Kallianpur, MK Chung, L Jehi, N Sharifi, ... BMC medicine 18, 1-8, 2020 | 424 | 2020 |
TSGene 2.0: an updated literature-based knowledgebase for tumor suppressor genes M Zhao, P Kim, R Mitra, J Zhao, Z Zhao Nucleic acids research 44 (D1), D1023-D1031, 2016 | 353 | 2016 |
Glioma progression is shaped by genetic evolution and microenvironment interactions FS Varn, KC Johnson, J Martinek, JT Huse, MLP Nasrallah, P Wesseling, ... Cell 185 (12), 2184-2199. e16, 2022 | 260 | 2022 |
Functional interrogation of DNA damage response variants with base editing screens R Cuella-Martin, SB Hayward, X Fan, X Chen, JW Huang, A Taglialatela, ... Cell 184 (4), 1081-1097. e19, 2021 | 194 | 2021 |
Efficient methods for identifying mutated driver pathways in cancer J Zhao, S Zhang, LY Wu, XS Zhang Bioinformatics 28 (22), 2940-2947, 2012 | 168 | 2012 |
Comprehensive characterization of protein–protein interactions perturbed by disease mutations F Cheng, J Zhao, Y Wang, W Lu, Z Liu, Y Zhou, WR Martin, R Wang, ... Nature genetics 53 (3), 342-353, 2021 | 160 | 2021 |
MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas B Oldrini, N Vaquero-Siguero, Q Mu, P Kroon, Y Zhang, M Galán-Ganga, ... Nature communications 11 (1), 3883, 2020 | 149 | 2020 |
Advances in computational approaches for prioritizing driver mutations and significantly mutated genes in cancer genomes F Cheng, J Zhao, Z Zhao Briefings in bioinformatics 17 (4), 642-656, 2016 | 149 | 2016 |
HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma models TTT Nguyen, Y Zhang, E Shang, C Shu, C Torrini, J Zhao, E Bianchetti, ... The Journal of clinical investigation 130 (7), 3699-3716, 2020 | 133 | 2020 |
Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy M Gromeier, MC Brown, G Zhang, X Lin, Y Chen, Z Wei, N Beaubier, ... Nature communications 12 (1), 352, 2021 | 109 | 2021 |
Extracellular Matrix/Integrin Signaling Promotes Resistance to Combined Inhibition of HER2 and PI3K in HER2+ Breast Cancer AB Hanker, MV Estrada, G Bianchini, PD Moore, J Zhao, F Cheng, ... Cancer research 77 (12), 3280-3292, 2017 | 99 | 2017 |
A gene gravity model for the evolution of cancer genomes: a study of 3,000 cancer genomes across 9 cancer types F Cheng, C Liu, CC Lin, J Zhao, P Jia, WH Li, Z Zhao PLoS computational biology 11 (9), e1004497, 2015 | 86 | 2015 |
STING agonist-loaded, CD47/PD-L1-targeting nanoparticles potentiate antitumor immunity and radiotherapy for glioblastoma P Zhang, A Rashidi, J Zhao, C Silvers, H Wang, B Castro, A Ellingwood, ... Nature communications 14 (1), 1610, 2023 | 79 | 2023 |
Proteome-scale investigation of protein allosteric regulation perturbed by somatic mutations in 7,000 cancer genomes Q Shen, F Cheng, H Song, W Lu, J Zhao, X An, M Liu, G Chen, Z Zhao, ... The American Journal of Human Genetics 100 (1), 5-20, 2017 | 78 | 2017 |
Single-cell characterization of macrophages in glioblastoma reveals MARCO as a mesenchymal pro-tumor marker AX Chen, RD Gartrell, J Zhao, PS Upadhyayula, W Zhao, J Yuan, ... Genome medicine 13 (1), 88, 2021 | 77 | 2021 |
ERK1/2 phosphorylation predicts survival following anti-PD-1 immunotherapy in recurrent glioblastoma VA Arrieta, AX Chen, JR Kane, SJ Kang, C Kassab, C Dmello, J Zhao, ... Nature cancer 2 (12), 1372-1386, 2021 | 74 | 2021 |
A MYC and RAS co-activation signature in localized prostate cancer drives bone metastasis and castration resistance JM Arriaga, S Panja, M Alshalalfa, J Zhao, M Zou, A Giacobbe, ... Nature Cancer 1 (11), 1082-1096, 2020 | 69 | 2020 |
A network-based drug repositioning infrastructure for precision cancer medicine through targeting significantly mutated genes in the human cancer genomes F Cheng, J Zhao, M Fooksa, Z Zhao Journal of the American Medical Informatics Association 23 (4), 681-691, 2016 | 58 | 2016 |
Systems biology-based investigation of cellular antiviral drug targets identified by gene-trap insertional mutagenesis F Cheng, JL Murray, J Zhao, J Sheng, Z Zhao, DH Rubin PLoS computational biology 12 (9), e1005074, 2016 | 56 | 2016 |