Interleukin-6 signalling: more than Jaks and STATs R Eulenfeld, A Dittrich, C Khouri, PJ Müller, B Mütze, A Wolf, F Schaper European journal of cell biology 91 (6-7), 486-495, 2012 | 203 | 2012 |
Response to IL-6 trans-and IL-6 classic signalling is determined by the ratio of the IL-6 receptor α to gp130 expression: fusing experimental insights and dynamic modelling H Reeh, N Rudolph, U Billing, H Christen, S Streif, E Bullinger, ... Cell Communication and Signaling 17, 1-21, 2019 | 151 | 2019 |
Glucocorticoids increase interleukin‐6–dependent gene induction by interfering with the expression of the suppressor of cytokine signaling 3 feedback inhibitor A Dittrich, C Khouri, SD Sackett, C Ehlting, O Böhmer, U Albrecht, ... Hepatology 55 (1), 256-266, 2012 | 53 | 2012 |
A simple work flow for biologically inspired model reduction-application to early JAK-STAT signaling T Quaiser, A Dittrich, F Schaper, M Mönnigmann BMC systems biology 5, 1-13, 2011 | 52 | 2011 |
Interleukin-6 influences stress-signalling by reducing the expression of the mTOR-inhibitor REDD1 in a STAT3-dependent manner J Pinno, H Bongartz, O Klepsch, N Wundrack, V Poli, F Schaper, A Dittrich Cellular signalling 28 (8), 907-916, 2016 | 48 | 2016 |
Model-driven experimental analysis of the function of SHP-2 in IL-6-induced Jak/STAT signaling A Dittrich, T Quaiser, C Khouri, D Görtz, M Mönnigmann, F Schaper Molecular BioSystems 8 (8), 2119-2134, 2012 | 47 | 2012 |
Robustness and information transfer within IL-6-induced JAK/STAT signalling U Billing, T Jetka, L Nortmann, N Wundrack, M Komorowski, S Waldherr, ... Communications biology 2 (1), 27, 2019 | 43 | 2019 |
Systems biology of IL-6, IL-12 family cytokines A Dittrich, W Hessenkemper, F Schaper Cytokine & Growth Factor Reviews 26 (5), 595-602, 2015 | 42 | 2015 |
JAK/STAT signalling–an executable model assembled from molecule-centred modules demonstrating a module-oriented database concept for systems and synthetic biology MA Blätke, A Dittrich, C Rohr, M Heiner, F Schaper, W Marwan Molecular BioSystems 9 (6), 1290-1307, 2013 | 39 | 2013 |
The tyrosine phosphatase SHP2 increases robustness and information transfer within IL-6-induced JAK/STAT signalling J Fiebelkow, A Guendel, B Guendel, N Mehwald, T Jetka, M Komorowski, ... Cell Communication and Signaling 19, 1-19, 2021 | 32 | 2021 |
Glucagon counteracts interleukin-6-dependent gene expression by redundant action of Epac and PKA C Khouri, A Dittrich, SD Sackett, B Denecke, C Trautwein, F Schaper Walter de Gruyter 392 (12), 1123-1134, 2011 | 14 | 2011 |
Intragenic regulation of SOCS3 isoforms O Klepsch, LS Namer, N Köhler, R Kaempfer, A Dittrich, F Schaper Cell Communication and Signaling 17, 1-15, 2019 | 13 | 2019 |
Quantitative proteomics and systems analysis of cultured H9C2 cardiomyoblasts during differentiation over time supports a ‘function follows form’model of differentiation C Kankeu, K Clarke, D Van Haver, K Gevaert, F Impens, A Dittrich, ... Molecular omics 14 (3), 181-196, 2018 | 13 | 2018 |
Hepatocyte KLF6 expression affects FXR signalling and the clinical course of primary sclerosing cholangitis S Sydor, P Manka, L van Buren, S Theurer, S Schwertheim, J Best, ... Liver International 40 (9), 2172-2181, 2020 | 6 | 2020 |
A two-level approach for fusing early signaling events and long term cellular responses N Rudolph, T Meyer, K Franzen, C Garbers, F Schaper, S Streif, A Dittrich, ... IFAC-PapersOnLine 48 (8), 1228-1233, 2015 | 5 | 2015 |
Non‐canonical STAT3 function reduces REDD1 transcription N Köhler, N Wundrack, S Schulz, F Bartonitz, F Schaper, A Dittrich The FEBS Journal 290 (7), 1765-1781, 2023 | 4 | 2023 |
Decoding cellular communication: An information theoretic perspective on cytokine and endocrine signaling F Schaper, T Jetka, A Dittrich Current Opinion in Endocrine and Metabolic Research 24, 100351, 2022 | 4 | 2022 |
JAK-STAT signalling as example for a database-supported modular modelling concept MA Blätke, A Dittrich, M Heiner, F Schaper, W Marwan International Conference on Computational Methods in Systems Biology, 362-365, 2012 | 4 | 2012 |
Quantification of membrane-bound cytokine receptors by calibrated flow cytometry N Miri, N Köhler, A Dittrich STAR protocols 4 (3), 102511, 2023 | 3 | 2023 |
Determination of protein turnover rates in the JAK/STAT pathway using a radioactive pulse-chase approach A Dittrich, E Siewert, F Schaper JAK-STAT Signalling: Methods and Protocols, 69-80, 2013 | 3 | 2013 |