Phase separation drives heterochromatin domain formation AR Strom, AV Emelyanov, M Mir, DV Fyodorov, X Darzacq, GH Karpen Nature 547 (7662), 241-245, 2017 | 1756 | 2017 |
Imaging dynamic and selective low-complexity domain interactions that control gene transcription S Chong, C Dugast-Darzacq, Z Liu, P Dong, GM Dailey, C Cattoglio, ... Science 361 (6400), eaar2555, 2018 | 899 | 2018 |
In vivo dynamics of RNA polymerase II transcription X Darzacq, Y Shav-Tal, V De Turris, Y Brody, SM Shenoy, RD Phair, ... Nature structural & molecular biology 14 (9), 796-806, 2007 | 780 | 2007 |
Cajal body‐specific small nuclear RNAs: a novel class of 2′‐O‐methylation and pseudouridylation guide RNAs X Darzacq, BE Jády, C Verheggen, AM Kiss, E Bertrand, T Kiss The EMBO journal, 2002 | 628 | 2002 |
CTCF and cohesin regulate chromatin loop stability with distinct dynamics AS Hansen, I Pustova, C Cattoglio, R Tjian, X Darzacq elife 6, e25776, 2017 | 587 | 2017 |
RNA polymerase II clustering through carboxy-terminal domain phase separation M Boehning, C Dugast-Darzacq, M Rankovic, AS Hansen, T Yu, ... Nature structural & molecular biology 25 (9), 833-840, 2018 | 569 | 2018 |
Overcoming the bottleneck to widespread testing: a rapid review of nucleic acid testing approaches for COVID-19 detection MN Esbin, ON Whitney, S Chong, A Maurer, X Darzacq, R Tjian Rna 26 (7), 771-783, 2020 | 561 | 2020 |
Dynamics of single mRNPs in nuclei of living cells Y Shav-Tal, X Darzacq, SM Shenoy, D Fusco, SM Janicki, DL Spector, ... science 304 (5678), 1797-1800, 2004 | 559 | 2004 |
Phase-separation mechanism for C-terminal hyperphosphorylation of RNA polymerase II H Lu, D Yu, AS Hansen, S Ganguly, R Liu, A Heckert, X Darzacq, Q Zhou Nature 558 (7709), 318-323, 2018 | 541 | 2018 |
Real-time dynamics of RNA polymerase II clustering in live human cells II Cisse, I Izeddin, SZ Causse, L Boudarene, A Senecal, L Muresan, ... Science 341 (6146), 664-667, 2013 | 537 | 2013 |
Evaluating phase separation in live cells: diagnosis, caveats, and functional consequences DT McSwiggen, M Mir, X Darzacq, R Tjian Genes & development 33 (23-24), 1619-1634, 2019 | 521 | 2019 |
Resolving the 3D landscape of transcription-linked mammalian chromatin folding THS Hsieh, C Cattoglio, E Slobodyanyuk, AS Hansen, OJ Rando, R Tjian, ... Molecular cell 78 (3), 539-553. e8, 2020 | 511 | 2020 |
Fast multicolor 3D imaging using aberration-corrected multifocus microscopy S Abrahamsson, J Chen, B Hajj, S Stallinga, AY Katsov, J Wisniewski, ... Nature methods 10 (1), 60-63, 2013 | 503 | 2013 |
Dynamic sorting of nuclear components into distinct nucleolar caps during transcriptional inhibition Y Shav-Tal, J Blechman, X Darzacq, C Montagna, BT Dye, JG Patton, ... Molecular biology of the cell 16 (5), 2395-2413, 2005 | 429 | 2005 |
FISH-quant: automatic counting of transcripts in 3D FISH images F Mueller, A Senecal, K Tantale, H Marie-Nelly, N Ly, O Collin, E Basyuk, ... Nature methods 10 (4), 277-278, 2013 | 410 | 2013 |
Gene expression is circular: factors for mRNA degradation also foster mRNA synthesis G Haimovich, DA Medina, SZ Causse, M Garber, G Millán-Zambrano, ... Cell 153 (5), 1000-1011, 2013 | 390 | 2013 |
A transgenic mouse for in vivo detection of endogenous labeled mRNA T Lionnet, K Czaplinski, X Darzacq, Y Shav-Tal, AL Wells, JA Chao, ... Nature methods 8 (2), 165-170, 2011 | 387 | 2011 |
Single-molecule tracking in live cells reveals distinct target-search strategies of transcription factors in the nucleus I Izeddin, V Récamier, L Bosanac, II Cissé, L Boudarene, ... Elife 3, e02230, 2014 | 340 | 2014 |
Modification of Sm small nuclear RNAs occurs in the nucleoplasmic Cajal body following import from the cytoplasm BE Jády, X Darzacq, KE Tucker, AG Matera, E Bertrand, T Kiss The EMBO journal, 2003 | 316 | 2003 |
Transcription factors modulate c-Fos transcriptional bursts A Senecal, B Munsky, F Proux, N Ly, FE Braye, C Zimmer, F Mueller, ... Cell reports 8 (1), 75-83, 2014 | 312 | 2014 |