Disease-modifying treatments for osteoarthritis (DMOADs) of the knee and hip: lessons learned from failures and opportunities for the future MA Karsdal, M Michaelis, C Ladel, AS Siebuhr, AR Bihlet, JR Andersen, ... Osteoarthritis and Cartilage 24 (12), 2013-2021, 2016 | 367 | 2016 |
Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis: The FORWARD Randomized Clinical Trial MC Hochberg, A Guermazi, H Guehring, A Aydemir, S Wax, ... Jama 322 (14), 1360-1370, 2019 | 279 | 2019 |
Treatment of symptomatic knee osteoarthritis with oral salmon calcitonin: results from two phase 3 trials MA Karsdal, I Byrjalsen, P Alexandersen, A Bihlet, JR Andersen, BJ Riis, ... Osteoarthritis and Cartilage 23 (4), 532-543, 2015 | 155 | 2015 |
A randomized, double-blind, multicenter, placebo-controlled study to evaluate the efficacy and safety of oral salmon calcitonin in the treatment of osteoporosis in … K Henriksen, I Byrjalsen, JR Andersen, AR Bihlet, LA Russo, ... Bone 91, 122-129, 2016 | 92 | 2016 |
OA phenotypes, rather than disease stage, drive structural progression–identification of structural progressors from 2 phase III randomized clinical studies with symptomatic … MA Karsdal, A Bihlet, I Byrjalsen, P Alexandersen, C Ladel, M Michaels, ... Osteoarthritis and Cartilage 23 (4), 550-558, 2015 | 76 | 2015 |
Long-term structural and symptomatic effects of intra-articular sprifermin in patients with knee osteoarthritis: 5-year results from the FORWARD study F Eckstein, MC Hochberg, H Guehring, F Moreau, V Ona, AR Bihlet, ... Annals of the Rheumatic Diseases 80 (8), 1062-1069, 2021 | 71 | 2021 |
Evaluation of the efficacy, safety and pharmacokinetic profile of oral recombinant human parathyroid hormone [rhPTH (1–31) NH 2] in postmenopausal women with osteoporosis K Henriksen, JR Andersen, BJ Riis, N Mehta, R Tavakkol, P Alexandersen, ... Bone 53 (1), 160-166, 2013 | 70 | 2013 |
The impact of clinical trial monitoring approaches on data integrity and cost—a review of current literature R Olsen, AR Bihlet, F Kalakou, JR Andersen European journal of clinical pharmacology 72, 399-412, 2016 | 68 | 2016 |
Impact of source data verification on data quality in clinical trials: an empirical post hoc analysis of three phase 3 randomized clinical trials JR Andersen, I Byrjalsen, A Bihlet, F Kalakou, HC Hoeck, G Hansen, ... British journal of clinical pharmacology 79 (4), 660-668, 2015 | 58 | 2015 |
Associations between biomarkers of bone and cartilage turnover, gender, pain categories and radiographic severity in knee osteoarthritis AR Bihlet, I Byrjalsen, AC Bay-Jensen, JR Andersen, C Christiansen, ... Arthritis research & therapy 21, 1-10, 2019 | 48 | 2019 |
Serum C-reactive protein metabolite (CRPM) is associated with incidence of contralateral knee osteoarthritis AC Bay-Jensen, A Bihlet, I Byrjalsen, JR Andersen, BJ Riis, ... Scientific Reports 11 (1), 6583, 2021 | 28 | 2021 |
OP0059 Efficacy and safety of intra-articular sprifermin in symptomatic radiographic knee osteoarthritis: pre-specified analysis of 3-year data from a 5-year randomised … M Hochberg, A Guermazi, H Guehring, A Aydemir, S Wax, ... Annals of the Rheumatic Diseases 77 (Suppl 2), 80-81, 2018 | 28 | 2018 |
Efficacy and safety of intra-articular Sprifermin in symptomatic radiographic knee osteoarthritis: pre-specified analysis of 3-year data from a 5-year randomized, placebo … M Hochberg, A Guermazi, H Guehring, A Aydemir, S Wax, ... Osteoarthritis and Cartilage 26, S26-S27, 2018 | 28* | 2018 |
Matrix metalloproteinase mediated type I collagen degradation is an independent predictor of increased risk of acute myocardial infarction in postmenopausal women DM Bertelsen, JS Neergaard, CL Bager, SH Nielsen, NH Secher, ... Scientific reports 8 (1), 5371, 2018 | 23 | 2018 |
Clinical and biochemical factors associated with risk of total joint replacement and radiographic progression in osteoarthritis: Data from two phase III clinical trials AR Bihlet, JJ Bjerre-Bastos, JR Andersen, I Byrjalsen, MA Karsdal, ... Seminars in arthritis and rheumatism 50 (6), 1374-1381, 2020 | 22 | 2020 |
Clinical Drug Development Using Dynamic Biomarkers to Enable Personalized Health Care in COPD AR Bihlet, MA Karsdal, AC Bay-Jensen, S Read, JH Kristensen, ... CHEST Journal 148 (1), 16-23, 2015 | 21 | 2015 |
Cohort Profile: The Prospective Epidemiological Risk Factor (PERF) study JS Neergaard, K Dragsbæk, SN Kehlet, HB Hansen, G Hansen, ... International Journal of Epidemiology, dyw251, 2016 | 20 | 2016 |
Does moderate intensity impact exercise and non-impact exercise induce acute changes in collagen biochemical markers related to osteoarthritis?–An exploratory randomized cross … JJ Bjerre-Bastos, HB Nielsen, JR Andersen, M Karsdal, AC Bay-Jensen, ... Osteoarthritis and Cartilage 29 (7), 986-994, 2021 | 16 | 2021 |
Identification of pain categories associated with change in pain in patients receiving placebo: data from two phase 3 randomized clinical trials in symptomatic knee osteoarthritis AR Bihlet, I Byrjalsen, AC Bay-Jensen, JR Andersen, C Christiansen, ... BMC Musculoskeletal Disorders 19, 1-11, 2018 | 14 | 2018 |
Efficacy and Safety of Intra-Articular Sprifermin in Symptomatic Radiographic Knee Osteoarthritis: Results of the 2-Year Primary Analysis from a 5Year Randomised, Placebo … M Hochberg, H Guehring, A Aydemir, S Wax, P Fleuranceau-Morel, ... Arthritis Rheumatol 69, S10, 2017 | 14 | 2017 |