Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression P Kuehl, J Zhang, Y Lin, J Lamba, M Assem, J Schuetz, PB Watkins, ... Nature genetics 27 (4), 383-391, 2001 | 2737 | 2001 |
Case definition and phenotype standardization in drug‐induced liver injury GP Aithal, PB Watkins, RJ Andrade, D Larrey, M Molokhia, H Takikawa, ... Clinical Pharmacology & Therapeutics 89 (6), 806-815, 2011 | 1188 | 2011 |
Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States N Chalasani, RJ Fontana, HL Bonkovsky, PB Watkins, T Davern, ... Gastroenterology 135 (6), 1924-1934. e4, 2008 | 1165 | 2008 |
Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: a new drug–drug interaction WC Lau, LA Waskell, PB Watkins, CJ Neer, K Horowitz, AS Hopp, AR Tait, ... Circulation 107 (1), 32-37, 2003 | 1123 | 2003 |
Hepatotoxic effects of tacrine administration in patients with Alzheimer's disease PB Watkins, HJ Zimmerman, MJ Knapp, SI Gracon, KW Lewis Jama 271 (13), 992-998, 1994 | 1057 | 1994 |
Features and outcomes of 899 patients with drug-induced liver injury: the DILIN prospective study N Chalasani, HL Bonkovsky, R Fontana, W Lee, A Stolz, J Talwalkar, ... Gastroenterology 148 (7), 1340-1352. e7, 2015 | 958 | 2015 |
Role of intestinal P‐glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine KS Lown, RR Mayo, AB Leichtman, H Hsiao, DK Turgeon, ... Clinical pharmacology & therapeutics 62 (3), 248-260, 1997 | 878 | 1997 |
Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression. KS Lown, DG Bailey, RJ Fontana, SK Janardan, CH Adair, LA Fortlage, ... The Journal of clinical investigation 99 (10), 2545-2553, 1997 | 866 | 1997 |
Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial PB Watkins, N Kaplowitz, JT Slattery, CR Colonese, SV Colucci, ... Jama 296 (1), 87-93, 2006 | 839 | 2006 |
Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance WC Lau, PA Gurbel, PB Watkins, CJ Neer, AS Hopp, DGM Carville, ... Circulation 109 (2), 166-171, 2004 | 791 | 2004 |
Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes. JC Kolars, P Schmiedlin-Ren, JD Schuetz, C Fang, PB Watkins The Journal of clinical investigation 90 (5), 1871-1878, 1992 | 674 | 1992 |
Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man. PB Watkins, SA Wrighton, EG Schuetz, DT Molowa, PS Guzelian The Journal of clinical investigation 80 (4), 1029-1036, 1987 | 623 | 1987 |
Drug-induced liver injury RJ Andrade, N Chalasani, ES Björnsson, A Suzuki, GA Kullak-Ublick, ... Nature Reviews Disease Primers 5 (1), 58, 2019 | 617 | 2019 |
Liver transplantation for acute liver failure from drug induced liver injury in the United States MW Russo, JA Galanko, R Shrestha, MW Fried, P Watkins Liver Transplantation 10 (8), 1018-1023, 2004 | 608 | 2004 |
Hepatic dysfunction associated with troglitazone PB Watkins, RW Whitcomb New England Journal of Medicine 338 (13), 916-917, 1998 | 601 | 1998 |
Incidence and etiology of drug-induced liver injury in mainland China T Shen, Y Liu, J Shang, Q Xie, J Li, M Yan, J Xu, J Niu, J Liu, PB Watkins, ... Gastroenterology 156 (8), 2230-2241. e11, 2019 | 593 | 2019 |
First-pass metabolism of cyclosporin by the gut JC Kolars, PB Watkins, RM Merion, WM Awni The Lancet 338 (8781), 1488-1490, 1991 | 536 | 1991 |
The barrier function of CYP3A4 and P-glycoprotein in the small bowel PB Watkins Advanced drug delivery reviews 27 (2-3), 161-170, 1997 | 531 | 1997 |
Drug-Induced Liver Injury Network (DILIN) prospective study: rationale, design and conduct RJ Fontana, PB Watkins, HL Bonkovsky, N Chalasani, T Davern, ... Drug safety 32, 55-68, 2009 | 519 | 2009 |
CYP3A gene expression in human gut epithelium JC Kolars, KS Lown, P Schmiedlin-Ren, M Ghosh, C Fang, SA Wrighton, ... Pharmacogenetics and Genomics 4 (5), 247-259, 1994 | 519 | 1994 |