John R. Horton
John R. Horton
MD Anderson Cancer Center-The University of Texas
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Zitiert von
Zitiert von
Selenomethionyl proteins produced for analysis by multiwavelength anomalous diffraction (MAD): a vehicle for direct determination of three‐dimensional structure.
WA Hendrickson, JR Horton, DM LeMaster
The EMBO journal 9 (5), 1665-1672, 1990
Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression
F Lan, RE Collins, R De Cegli, R Alpatov, JR Horton, X Shi, O Gozani, ...
Nature 448 (7154), 718-722, 2007
The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix
H Hashimoto, JR Horton, X Zhang, M Bostick, SE Jacobsen, X Cheng
Nature 455 (7214), 826-829, 2008
Structural basis for the product specificity of histone lysine methyltransferases
X Zhang, Z Yang, SI Khan, JR Horton, H Tamaru, EU Selker, X Cheng
Molecular cell 12 (1), 177-185, 2003
Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases
JR Horton, AK Upadhyay, HH Qi, X Zhang, Y Shi, X Cheng
Nature structural & molecular biology 17 (1), 38-43, 2010
Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294
Y Chang, X Zhang, JR Horton, AK Upadhyay, A Spannhoff, J Liu, ...
Nature structural & molecular biology 16 (3), 312-317, 2009
The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin
FE Reyes-Turcu, JR Horton, JE Mullally, A Heroux, X Cheng, ...
Cell 124 (6), 1197-1208, 2006
Structure of the Neurospora SET domain protein DIM-5, a histone H3 lysine methyltransferase
X Zhang, H Tamaru, SI Khan, JR Horton, LJ Keefe, EU Selker, X Cheng
Cell 111 (1), 117-127, 2002
The ankyrin repeats of G9a and GLP histone methyltransferases are mono-and dimethyllysine binding modules
RE Collins, JP Northrop, JR Horton, DY Lee, X Zhang, MR Stallcup, ...
Nature structural & molecular biology 15 (3), 245-250, 2008
A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability
PO Estève, Y Chang, M Samaranayake, AK Upadhyay, JR Horton, ...
Nature structural & molecular biology 18 (1), 42-48, 2011
Structural basis for the versatile and methylation-dependent binding of CTCF to DNA
H Hashimoto, D Wang, JR Horton, X Zhang, VG Corces, X Cheng
Molecular cell 66 (5), 711-720. e3, 2017
MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a
Y Chang, L Sun, K Kokura, JR Horton, M Fukuda, A Espejo, V Izumi, ...
Nature communications 2 (1), 533, 2011
Dimeric Galectin-8 induces phosphatidylserine exposure in leukocytes through polylactosamine recognition by the C-terminal domain
SR Stowell, CM Arthur, KA Slanina, JR Horton, DF Smith, RD Cummings
Journal of Biological Chemistry 283 (29), 20547-20559, 2008
UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications
H Hashimoto, JR Horton, X Zhang, X Cheng
Epigenetics 4 (1), 8-14, 2009
Structures of Hha I methyltransferase complexed with substrates containing mismatches at the target base
M O'Gara, JR Horton, RJ Roberts, X Cheng
nature structural biology 5 (10), 872-877, 1998
Structure and substrate recognition of the Escherichia coli DNA adenine methyltransferase
JR Horton, K Liebert, M Bekes, A Jeltsch, X Cheng
Journal of molecular biology 358 (2), 559-570, 2006
Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase
K Sawada, Z Yang, JR Horton, RE Collins, X Zhang, X Cheng
Journal of Biological Chemistry 279 (41), 43296-43306, 2004
Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases
Y Chang, T Ganesh, JR Horton, A Spannhoff, J Liu, A Sun, X Zhang, ...
Journal of molecular biology 400 (1), 1-7, 2010
SETD3 is an actin histidine methyltransferase that prevents primary dystocia
AW Wilkinson, J Diep, S Dai, S Liu, YS Ooi, D Song, TM Li, JR Horton, ...
Nature 565 (7739), 372-376, 2019
Transition from nonspecific to specific DNA interactions along the substrate-recognition pathway of dam methyltransferase
JR Horton, K Liebert, S Hattman, A Jeltsch, X Cheng
Cell 121 (3), 349-361, 2005
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