Arumugam Rajavelu
Zitiert von
Zitiert von
The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation
A Dhayalan, A Rajavelu, P Rathert, R Tamas, RZ Jurkowska, S Ragozin, ...
Journal of Biological Chemistry 285 (34), 26114-26120, 2010
Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail
Y Zhang, R Jurkowska, S Soeroes, A Rajavelu, A Dhayalan, I Bock, ...
Nucleic acids research 38 (13), 4246-4253, 2010
Targeted methylation and gene silencing of VEGF-A in human cells by using a designed Dnmt3a–Dnmt3L single-chain fusion protein with increased DNA methylation activity
AN Siddique, S Nunna, A Rajavelu, Y Zhang, RZ Jurkowska, R Reinhardt, ...
Journal of molecular biology 425 (3), 479-491, 2013
Oligomerization and binding of the Dnmt3a DNA methyltransferase to parallel DNA molecules: heterochromatic localization and role of Dnmt3L
RZ Jurkowska, A Rajavelu, N Anspach, C Urbanke, G Jankevicius, ...
Journal of Biological Chemistry 286 (27), 24200-24207, 2011
Synthesis and Evaluation of Analogues of N-Phthaloyl-l-tryptophan (RG108) as Inhibitors of DNA Methyltransferase 1
S Asgatay, C Champion, G Marloie, T Drujon, C Senamaud-Beaufort, ...
Journal of medicinal chemistry 57 (2), 421-434, 2014
C5‐DNA methyltransferase inhibitors: from screening to effects on zebrafish embryo development
A Ceccaldi, A Rajavelu, C Champion, C Rampon, R Jurkowska, ...
Chembiochem 12 (9), 1337-1345, 2011
Regulation of DNA methylation patterns by CK2-mediated phosphorylation of Dnmt3a
R Deplus, L Blanchon, A Rajavelu, A Boukaba, M Defrance, J Luciani, ...
Cell reports 8 (3), 743-753, 2014
The inhibition of the mammalian DNA methyltransferase 3a (Dnmt3a) by dietary black tea and coffee polyphenols
A Rajavelu, Z Tulyasheva, R Jaiswal, A Jeltsch, N Kuhnert
BMC biochemistry 12, 1-8, 2011
Rapid synthesis of new DNMT inhibitors derivatives of procainamide
L Halby, C Champion, C Sénamaud‐Beaufort, S Ajjan, T Drujon, ...
Chembiochem 13 (1), 157-165, 2012
Identification of novel inhibitors of DNA methylation by screening of a chemical library
A Ceccaldi, A Rajavelu, S Ragozin, C Sénamaud-Beaufort, P Bashtrykov, ...
ACS chemical biology 8 (3), 543-548, 2013
Design, Synthesis and Biological Evaluation of 4‐Amino‐N‐(4‐aminophenyl)benzamide Analogues of Quinoline‐Based SGI‐1027 as Inhibitors of DNA Methylation
E Rilova, A Erdmann, C Gros, V Masson, Y Aussagues, ...
ChemMedChem 9 (3), 590-601, 2014
Genetic and epigenetic mechanisms in the development of arteriovenous malformations in the brain
JM Thomas, S Surendran, M Abraham, A Rajavelu, CC Kartha
Clinical epigenetics 8, 1-8, 2016
Function and disruption of DNA methyltransferase 3a cooperative DNA binding and nucleoprotein filament formation
A Rajavelu, RZ Jurkowska, J Fritz, A Jeltsch
Nucleic acids research 40 (2), 569-580, 2012
Cooperative DNA binding and protein/DNA fiber formation increases the activity of the Dnmt3a DNA methyltransferase
M Emperle, A Rajavelu, R Reinhardt, RZ Jurkowska, A Jeltsch
Journal of Biological Chemistry 289 (43), 29602-29613, 2014
The DNMT3A R882H mutant displays altered flanking sequence preferences
M Emperle, A Rajavelu, S Kunert, PB Arimondo, R Reinhardt, ...
Nucleic acids research 46 (6), 3130-3139, 2018
Localisation of Plasmodium falciparum uroporphyrinogen III decarboxylase of the heme-biosynthetic pathway in the apicoplast and characterisation of its catalytic properties
VA Nagaraj, R Arumugam, NR Chandra, D Prasad, PN Rangarajan, ...
International journal for parasitology 39 (5), 559-568, 2009
Unique properties of Plasmodium falciparum porphobilinogen deaminase
VA Nagaraj, R Arumugam, B Gopalakrishnan, YS Jyothsna, ...
Journal of biological chemistry 283 (1), 437-444, 2008
Targeted mutagenesis results in an activation of DNA methyltransferase 1 and confirms an autoinhibitory role of its RFTS domain
P Bashtrykov, A Rajavelu, B Hackner, S Ragozin, T Carell, A Jeltsch
Chembiochem 15 (5), 743-748, 2014
Protoporphyrinogen IX oxidase from Plasmodium falciparum is anaerobic and is localized to the mitochondrion
VA Nagaraj, R Arumugam, D Prasad, PN Rangarajan, G Padmanaban
Molecular and biochemical parasitology 174 (1), 44-52, 2010
Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2
A Rajavelu, C Lungu, M Emperle, M Dukatz, A Bröhm, J Broche, I Hanelt, ...
Nucleic acids research 46 (17), 9044-9056, 2018
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