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Alexander P Browning
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Identifiability analysis for stochastic differential equation models in systems biology
AP Browning, DJ Warne, K Burrage, RE Baker, MJ Simpson
Journal of the Royal Society Interface 17 (173), 20200652, 2020
762020
Quantitative analysis of tumour spheroid structure
AP Browning, JA Sharp, RJ Murphy, G Gunasingh, B Lawson, K Burrage, ...
Elife 10, e73020, 2021
492021
Parameter identifiability and model selection for sigmoid population growth models
MJ Simpson, AP Browning, DJ Warne, OJ Maclaren, RE Baker
Journal of theoretical biology 535, 110998, 2022
462022
Inferring parameters for a lattice-free model of cell migration and proliferation using experimental data
AP Browning, SW McCue, RN Binny, MJ Plank, ET Shah, MJ Simpson
Journal of Theoretical Biology 437, 251-260, 2018
422018
A Bayesian sequential learning framework to parameterise continuum models of melanoma invasion into human skin
AP Browning, P Haridas, M Simpson
Bulletin of Mathematical Biology 81, 676-698, 2019
392019
Designing and interpreting 4D tumour spheroid experiments
RJ Murphy, AP Browning, G Gunasingh, NK Haass, MJ Simpson
Communications Biology 5 (1), 91, 2022
322022
Optimal control of acute myeloid leukaemia
JA Sharp, AP Browning, T Mapder, K Burrage, MJ Simpson
Journal of Theoretical Biology 470, 30-42, 2019
312019
A Bayesian computational approach to explore the optimal duration of a cell proliferation assay
AP Browning, SW McCue, MJ Simpson
Bulletin of Mathematical Biology 79 (8), 1888-1906, 2017
262017
A stochastic mathematical model of 4D tumour spheroids with real-time fluorescent cell cycle labelling
JJ Klowss, AP Browning, RJ Murphy, EJ Carr, MJ Plank, G Gunasingh, ...
Journal of the Royal Society Interface 19 (189), 20210903, 2022
242022
Model-based data analysis of tissue growth in thin 3D printed scaffolds
AP Browning, OJ Maclaren, PR Buenzli, M Lanaro, MC Allenby, ...
Journal of Theoretical Biology 528, 110852, 2021
242021
Designing combination therapies using multiple optimal controls
JA Sharp, AP Browning, T Mapder, CM Baker, K Burrage, MJ Simpson
Journal of Theoretical Biology 497, 110277, 2020
202020
Persistence as an optimal hedging strategy
AP Browning, JA Sharp, T Mapder, CM Baker, K Burrage, MJ Simpson
Biophysical Journal, 2021
192021
Reversible signal transmission in an active mechanical metamaterial
AP Browning, FG Woodhouse, MJ Simpson
Proceedings of the Royal Society A: Mathematical Physical and Engineering …, 2019
152019
Profile likelihood analysis for a stochastic model of diffusion in heterogeneous media
MJ Simpson, AP Browning, C Drovandi, EJ Carr, OJ Maclaren, RE Baker
Proceedings of the Royal Society A 477 (2250), 20210214, 2021
132021
Identifying density-dependent interactions in collective cell behaviour
AP Browning, W Jin, MJ Plank, MJ Simpson
Journal of The Royal Society Interface 17 (165), 20200143, 2020
122020
Parameter estimation and uncertainty quantification using information geometry
JA Sharp, AP Browning, K Burrage, MJ Simpson
Journal of the Royal Society Interface 19 (189), 20210940, 2022
102022
Three-dimensional experiments and individual based simulations show that cell proliferation drives melanoma nest formation in human skin tissue
P Haridas, AP Browning, J McGovern, S McElwain, M Simpson
BMC Systems Biology 12 (1), 34, 2018
102018
Geometric analysis enables biological insight from complex non-identifiable models using simple surrogates
AP Browning, MJ Simpson
PLoS Computational Biology 19 (1), e1010844, 2023
92023
Rapid Optical Clearing for Semi-High-Throughput Analysis of Tumor Spheroids
G Gunasingh, AP Browning, NK Haass
JoVE (Journal of Visualized Experiments), e64103, 2022
62022
Efficient inference and identifiability analysis for differential equation models with random parameters
AP Browning, C Drovandi, IW Turner, AL Jenner, MJ Simpson
PLOS Computational Biology 18 (11), e1010734, 2022
52022
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