Alba Rodríguez Meira
Alba Rodríguez Meira
Dana Farber Cancer Institute
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Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia
A Giustacchini, S Thongjuea, N Barkas, PS Woll, BJ Povinelli, CAG Booth, ...
Nature medicine 23 (6), 692-702, 2017
Unravelling intratumoral heterogeneity through high-sensitivity single-cell mutational analysis and parallel RNA sequencing
A Rodriguez-Meira, G Buck, SA Clark, BJ Povinelli, V Alcolea, E Louka, ...
Molecular cell 73 (6), 1292-1305. e8, 2019
Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion
VTM Nguyen, I Barozzi, M Faronato, Y Lombardo, JH Steel, N Patel, ...
Nature communications 6 (1), 10044, 2015
Single-cell analyses reveal megakaryocyte-biased hematopoiesis in myelofibrosis and identify mutant clone-specific targets
B Psaila, G Wang, A Rodriguez-Meira, R Li, EF Heuston, L Murphy, D Yee, ...
Molecular cell 78 (3), 477-492. e8, 2020
SREBP1 drives Keratin-80-dependent cytoskeletal changes and invasive behavior in endocrine-resistant ERα breast cancer
Y Perone, AJ Farrugia, A Rodríguez-Meira, B Győrffy, C Ion, A Uggetti, ...
Nature communications 10 (1), 2115, 2019
Single cell analysis of normal and leukemic hematopoiesis
BJ Povinelli, A Rodriguez-Meira, AJ Mead
Molecular aspects of medicine 59, 85-94, 2018
Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development
A Roy, G Wang, D Iskander, S O’Byrne, N Elliott, J O’Sullivan, G Buck, ...
Cell Reports 36 (11), 109698, 2021
TARGET-Seq: A Protocol for High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing
A Rodriguez-Meira, J O’Sullivan, H Rahman, AJ Mead
STAR Protocols, 100125, 2020
Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution
A Rodriguez-Meira, R Norfo, S Wen, AL Chédeville, H Rahman, ...
Nature genetics 55 (9), 1531-1541, 2023
Tumoral stem cell reprogramming as a driver of cancer: Theory, biological models, implications in cancer therapy
C Vicente-Dueñas, J Hauer, L Ruiz-Roca, D Ingenhag, ...
Seminars in cancer biology 32, 3-9, 2015
Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia
E Louka, B Povinelli, A Rodriguez-Meira, G Buck, WX Wen, G Wang, ...
Journal of Experimental Medicine 218 (2), 2019
C/EBPα and GATA-2 mutations induce bilineage acute erythroid leukemia through transformation of a neomorphic neutrophil-erythroid progenitor
C Di Genua, S Valletta, M Buono, B Stoilova, C Sweeney, ...
Cancer cell 37 (5), 690-704. e8, 2020
Deciphering TP53 mutant Cancer Evolution with Single-Cell Multi-Omics
A Rodriguez-Meira, R Norfo, WX Wen, AL Chédeville, H Rahman, ...
BiorXiv, 2022.03. 28.485984, 2022
Effects of Tamoxifen on the Mutant Allele Burden and Disease Course in Patients with Myeloproliferative Neoplasms-Results of the Tamarin Study
C Harrison, J Baxter, RH Boucher, T McKerrell, A Jackson, RS Fletcher, ...
BLOOD 136, 2020
Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation
C Di Genua, R Norfo, A Rodriguez-Meira, WX Wen, R Drissen, ...
haematologica 104 (11), 2215, 2019
Single-Cell Multi-Omics Reveals the Genetic, Cellular and Molecular Landscape of TP53 Mutated Leukemic Transformation in MPN
A Rodriguez-Meira, H Rahman, R Norfo, W Wen, A Chédeville, ...
Blood 138 (Supplement 1), 3-3, 2021
Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner
TC Luis, N Barkas, J Carrelha, A Giustacchini, S Mazzi, R Norfo, B Wu, ...
Nature Communications 14 (1), 6062, 2023
Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors
WH Neo, Y Meng, A Rodriguez-Meira, MZH Fadlullah, CAG Booth, ...
Nature Communications 12 (1), 7019, 2021
Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy
AS Schnegg-Kaufmann, JAI Thoms, GS Bhuyan, HR Hampton, ...
Blood 141 (11), 1316-1321, 2023
Single-cell analyses reveal aberrant pathways for megakaryocyte-biased hematopoiesis in myelofibrosis and identify mutant clone-specific targets
B Psaila, G Wang, AR Meira, EF Heuston, R Li, J O’Sullivan, N Sousos, ...
bioRxiv, 642819, 2019
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