Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells SM Elbashir, J Harborth, W Lendeckel, A Yalcin, K Weber, T Tuschl nature 411 (6836), 494-498, 2001 | 14258 | 2001 |
Identification of novel genes coding for small expressed RNAs M Lagos-Quintana, R Rauhut, W Lendeckel, T Tuschl Science 294 (5543), 853-858, 2001 | 6805 | 2001 |
RNA interference is mediated by 21-and 22-nucleotide RNAs SM Elbashir, W Lendeckel, T Tuschl Genes & development 15 (2), 188-200, 2001 | 5711 | 2001 |
Silencing of microRNAs in vivo with ‘antagomirs’ J Krützfeldt, N Rajewsky, R Braich, KG Rajeev, T Tuschl, M Manoharan, ... nature 438 (7068), 685-689, 2005 | 5099 | 2005 |
RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals PD Zamore, T Tuschl, PA Sharp, DP Bartel cell 101 (1), 25-33, 2000 | 4604 | 2000 |
Human microRNA targets B John, AJ Enright, A Aravin, T Tuschl, C Sander, DS Marks PLoS biology 2 (11), e363, 2004 | 4545 | 2004 |
A mammalian microRNA expression atlas based on small RNA library sequencing P Landgraf, M Rusu, R Sheridan, A Sewer, N Iovino, A Aravin, S Pfeffer, ... Cell 129 (7), 1401-1414, 2007 | 4515 | 2007 |
Identification of tissue-specific microRNAs from mouse M Lagos-Quintana, R Rauhut, A Yalcin, J Meyer, W Lendeckel, T Tuschl Current biology 12 (9), 735-739, 2002 | 4468 | 2002 |
A Cellular Function for the RNA-Interference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA G Hutvagner, J McLachlan, AE Pasquinelli, É Bálint, T Tuschl, PD Zamore Science 293 (5531), 834-838, 2001 | 3919 | 2001 |
MicroRNA Targets in Drosophila A Enright, B John, U Gaul, T Tuschl, C Sander, D Marks Genome biology 4, 1-27, 2003 | 3905 | 2003 |
Mechanisms of gene silencing by double-stranded RNA G Meister, T Tuschl Nature 431 (7006), 343-349, 2004 | 3448 | 2004 |
Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP M Hafner, M Landthaler, L Burger, M Khorshid, J Hausser, P Berninger, ... Cell 141 (1), 129-141, 2010 | 3276 | 2010 |
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts T Thum, C Gross, J Fiedler, T Fischer, S Kissler, M Bussen, P Galuppo, ... Nature 456 (7224), 980-984, 2008 | 2885 | 2008 |
A pancreatic islet-specific microRNA regulates insulin secretion MN Poy, L Eliasson, J Krutzfeldt, S Kuwajima, X Ma, PE Macdonald, ... Nature 432 (7014), 226-230, 2004 | 2736 | 2004 |
Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs G Meister, M Landthaler, A Patkaniowska, Y Dorsett, G Teng, T Tuschl Molecular cell 15 (2), 185-197, 2004 | 2616 | 2004 |
A uniform system for microRNA annotation V Ambros, B Bartel, DP Bartel, CB Burge, JC Carrington, X Chen, ... Rna 9 (3), 277-279, 2003 | 2576 | 2003 |
Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate SM Elbashir, J Martinez, A Patkaniowska, W Lendeckel, T Tuschl The EMBO journal 20 (23), 6877-6888, 2001 | 2566 | 2001 |
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi J Martinez, A Patkaniowska, H Urlaub, R Lührmann, T Tuschl Cell 110 (5), 563-574, 2002 | 2310 | 2002 |
Identification of virus-encoded microRNAs S Pfeffer, M Zavolan, FA Grässer, M Chien, JJ Russo, J Ju, B John, ... Science 304 (5671), 734-736, 2004 | 2108 | 2004 |
A census of human RNA-binding proteins S Gerstberger, M Hafner, T Tuschl Nature Reviews Genetics 15 (12), 829-845, 2014 | 1976 | 2014 |