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Hans-Guido Wendel
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Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy
HG Wendel, E Stanchina, JS Fridman, A Malina, S Ray, S Kogan, ...
Nature 428 (6980), 332-337, 2004
12122004
Clinical and biological correlates of neurotoxicity associated with CAR T-cell therapy in patients with B-cell acute lymphoblastic leukemia
BD Santomasso, JH Park, D Salloum, I Riviere, J Flynn, E Mead, E Halton, ...
Cancer discovery 8 (8), 958-971, 2018
8042018
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer
AL Wolfe, K Singh, Y Zhong, P Drewe, VK Rajasekhar, VR Sanghvi, ...
Nature 513 (7516), 65-70, 2014
6702014
Dissecting eIF4E action in tumorigenesis
HG Wendel, RLA Silva, A Malina, JR Mills, H Zhu, T Ueda, ...
Genes & development 21 (24), 3232-3237, 2007
5842007
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development
A Ortega-Molina, IW Boss, A Canela, H Pan, Y Jiang, C Zhao, M Jiang, ...
Nature medicine 21 (10), 1199-1208, 2015
4562015
Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia
KJ Mavrakis, AL Wolfe, E Oricchio, T Palomero, K De Keersmaecker, ...
Nature cell biology 12 (4), 372-379, 2010
4302010
Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model
ME Bordeleau, F Robert, B Gerard, L Lindqvist, SMH Chen, HG Wendel, ...
The Journal of clinical investigation 118 (7), 2651-2660, 2008
3932008
GPRC5D is a target for the immunotherapy of multiple myeloma with rationally designed CAR T cells
EL Smith, K Harrington, M Staehr, R Masakayan, J Jones, TJ Long, KY Ng, ...
Science translational medicine 11 (485), eaau7746, 2019
3452019
A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL)
KJ Mavrakis, J Van Der Meulen, AL Wolfe, X Liu, E Mets, T Taghon, ...
Nature genetics 43 (7), 673-678, 2011
3342011
mTORC1 promotes survival through translational control of Mcl-1
JR Mills, Y Hippo, F Robert, SMH Chen, A Malina, CJ Lin, U Trojahn, ...
Proceedings of the National Academy of Sciences 105 (31), 10853-10858, 2008
3242008
CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas
Y Jiang, A Ortega-Molina, H Geng, HY Ying, K Hatzi, S Parsa, D McNally, ...
Cancer discovery 7 (1), 38-53, 2017
2752017
Loss of the HVEM tumor suppressor in lymphoma and restoration by modified CAR-T cells
M Boice, D Salloum, F Mourcin, V Sanghvi, R Amin, E Oricchio, M Jiang, ...
Cell 167 (2), 405-418. e13, 2016
2752016
The Eph-receptor A7 is a soluble tumor suppressor for follicular lymphoma
E Oricchio, G Nanjangud, AL Wolfe, JH Schatz, KJ Mavrakis, M Jiang, ...
Cell 147 (3), 554-564, 2011
2262011
The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia
J Van der Meulen, V Sanghvi, K Mavrakis, K Durinck, F Fang, ...
Blood, The Journal of the American Society of Hematology 125 (1), 13-21, 2015
2102015
Small cell lung cancer: can recent advances in biology and molecular biology be translated into improved outcomes?
PA Bunn Jr, JD Minna, A Augustyn, AF Gazdar, Y Ouadah, MA Krasnow, ...
Journal of Thoracic Oncology 11 (4), 453-474, 2016
2092016
Loss of p53 impedes the antileukemic response to BCR-ABL inhibition
HG Wendel, E de Stanchina, E Cepero, S Ray, M Emig, JS Fridman, ...
Proceedings of the National Academy of Sciences 103 (19), 7444-7449, 2006
1732006
RiboDiff: detecting changes of mRNA translation efficiency from ribosome footprints
Y Zhong, T Karaletsos, P Drewe, VT Sreedharan, D Kuo, K Singh, ...
Bioinformatics 33 (1), 139-141, 2017
1722017
Defining an optimal dual-targeted CAR T-cell therapy approach simultaneously targeting BCMA and GPRC5D to prevent BCMA escape–driven relapse in multiple myeloma
C Fernández de Larrea, M Staehr, AV Lopez, KY Ng, Y Chen, ...
Blood cancer discovery 1 (2), 146-154, 2020
165*2020
Endogenous expression of HrasG12V induces developmental defects and neoplasms with copy number imbalances of the oncogene
X Chen, N Mitsutake, K LaPerle, N Akeno, P Zanzonico, VA Longo, ...
Proceedings of the National Academy of Sciences 106 (19), 7979-7984, 2009
1592009
Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma
JH Schatz, E Oricchio, AL Wolfe, M Jiang, I Linkov, J Maragulia, W Shi, ...
Journal of experimental medicine 208 (9), 1799-1807, 2011
1422011
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