H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1 RZ Jurkowska, S Qin, G Kungulovski, W Tempel, Y Liu, P Bashtrykov, ... Nature communications 8 (1), 2057, 2017 | 82 | 2017 |
The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes E Davydova, T Shimazu, MK Schuhmacher, ME Jakobsson, ... Nature communications 12 (1), 891, 2021 | 79 | 2021 |
Activity and specificity of the human SUV39H2 protein lysine methyltransferase MK Schuhmacher, S Kudithipudi, D Kusevic, S Weirich, A Jeltsch Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1849 (1), 55-63, 2015 | 55 | 2015 |
Specificity of the SUV4–20H1 and SUV4–20H2 protein lysine methyltransferases and methylation of novel substrates S Weirich, S Kudithipudi, A Jeltsch Journal of Molecular Biology 428 (11), 2344-2358, 2016 | 41 | 2016 |
Somatic cancer mutations in the MLL3-SET domain alter the catalytic properties of the enzyme S Weirich, S Kudithipudi, I Kycia, A Jeltsch Clinical epigenetics 7, 1-9, 2015 | 41 | 2015 |
Recognition of nonproline N-terminal residues by the Pro/N-degron pathway C Dong, SJ Chen, A Melnykov, S Weirich, K Sun, A Jeltsch, A Varshavsky, ... Proceedings of the National Academy of Sciences 117 (25), 14158-14167, 2020 | 40 | 2020 |
Specificity analysis of protein lysine methyltransferases using SPOT peptide arrays S Kudithipudi, D Kusevic, S Weirich, A Jeltsch Journal of visualized experiments: JoVE, 2014 | 32 | 2014 |
Structure, activity and function of the Suv39h1 and Suv39h2 protein lysine methyltransferases S Weirich, MS Khella, A Jeltsch Life 11 (7), 703, 2021 | 31 | 2021 |
Improving the resistance of a eukaryotic β-barrel protein to thermal and chemical perturbations D Gessmann, F Mager, H Naveed, T Arnold, S Weirich, D Linke, J Liang, ... Journal of molecular biology 413 (1), 150-161, 2011 | 27 | 2011 |
A functional LSD1 coregulator screen reveals a novel transcriptional regulatory cascade connecting R-loop homeostasis with epigenetic regulation S Pinter, F Knodel, M Choudalakis, P Schnee, C Kroll, M Fuchs, A Broehm, ... Nucleic Acids Research 49 (8), 4350-4370, 2021 | 23 | 2021 |
Somatic cancer mutations in the MLL 1 histone methyltransferase modulate its enzymatic activity and dependence on the WDR 5/RBBP 5/ASH 2L complex S Weirich, S Kudithipudi, A Jeltsch Molecular oncology 11 (4), 373-387, 2017 | 23 | 2017 |
Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate MK Schuhmacher, S Beldar, MS Khella, A Bröhm, J Ludwig, W Tempel, ... Communications Biology 3 (1), 511, 2020 | 21 | 2020 |
Analysis of the substrate specificity of the SMYD2 protein lysine methyltransferase and discovery of novel non‐histone substrates S Weirich, MK Schuhmacher, S Kudithipudi, C Lungu, AD Ferguson, ... Chembiochem 21 (1-2), 256-264, 2020 | 19 | 2020 |
The Legionella pneumophila methyltransferase RomA methylates also non-histone proteins during infection MK Schuhmacher, M Rolando, A Bröhm, S Weirich, S Kudithipudi, ... Journal of molecular biology 430 (13), 1912-1925, 2018 | 19 | 2018 |
Somatic cancer mutations in the SUV420H1 protein lysine methyltransferase modulate its catalytic activity A Bröhm, H Elsawy, P Rathert, S Kudithipudi, T Schoch, MK Schuhmacher, ... Journal of molecular biology 431 (17), 3068-3080, 2019 | 18 | 2019 |
A loss-of-function variant in SUV39H2 identified in autism-spectrum disorder causes altered H3K9 trimethylation and dysregulation of protocadherin β-cluster … S Balan, Y Iwayama, T Ohnishi, M Fukuda, A Shirai, A Yamada, S Weirich, ... Molecular Psychiatry 26 (12), 7550-7559, 2021 | 17 | 2021 |
CRL2ZER1/ZYG11B recognizes small N-terminal residues for degradation Y Li, Y Zhao, X Yan, C Ye, S Weirich, B Zhang, X Wang, L Song, C Jiang, ... Nature Communications 13 (1), 7636, 2022 | 13 | 2022 |
Development of an epigenetic tetracycline sensor system based on DNA methylation T Ullrich, S Weirich, A Jeltsch PLoS One 15 (5), e0232701, 2020 | 11 | 2020 |
Investigation of the methylation of Numb by the SET8 protein lysine methyltransferase S Weirich, D Kusevic, S Kudithipudi, A Jeltsch Scientific Reports 5 (1), 13813, 2015 | 11 | 2015 |
Specificity analysis of protein methyltransferases and discovery of novel substrates using SPOT peptide arrays S Weirich, A Jeltsch Histone Methyltransferases: Methods and Protocols, 313-325, 2022 | 9 | 2022 |