| Mathematical modeling of tumor-associated macrophage interactions with the cancer microenvironment G Mahlbacher, LT Curtis, J Lowengrub, HB Frieboes Journal for immunotherapy of cancer 6 (1), 10, 2018 | 102 | 2018 |
| Enhanced uptake and transport of PLGA-modified nanoparticles in cervical cancer LB Sims, LT Curtis, HB Frieboes, JM Steinbach-Rankins Journal of nanobiotechnology 14 (1), 33, 2016 | 82 | 2016 |
| Macrophage polarization contributes to the anti-Tumoral efficacy of Mesoporous Nanovectors loaded with albumin-bound Paclitaxel F Leonard, LT Curtis, MJ Ware, T Nosrat, X Liu, K Yokoi, HB Frieboes, ... Frontiers in immunology 8, 693, 2017 | 61 | 2017 |
| Enhanced performance of macrophage-encapsulated nanoparticle albumin-bound-paclitaxel in hypo-perfused cancer lesions F Leonard, LT Curtis, P Yesantharao, T Tanei, JF Alexander, M Wu, ... Nanoscale 8 (25), 12544-12552, 2016 | 61 | 2016 |
| Computational modeling of tumor response to drug release from vasculature-bound nanoparticles LT Curtis, M Wu, J Lowengrub, P Decuzzi, HB Frieboes PloS one 10 (12), 2015 | 60 | 2015 |
| An interdisciplinary computational/experimental approach to evaluate drug-loaded gold nanoparticle tumor cytotoxicity LT Curtis, CG England, M Wu, J Lowengrub, HB Frieboes Nucleic Acids Research 11 (3), 197-216, 2016 | 49 | 2016 |
| Nonlinear response to cancer nanotherapy due to macrophage interactions revealed by mathematical modeling and evaluated in a murine model via CRISPR-modulated macrophage … F Leonard, LT Curtis, AR Hamed, C Zhang, E Chau, D Sieving, B Godin, ... Cancer Immunology, Immunotherapy, 1-14, 2020 | 36 | 2020 |
| The tumor microenvironment as a barrier to cancer nanotherapy LT Curtis, HB Frieboes Systems Biology of Tumor Microenvironment, 165-190, 2016 | 23 | 2016 |
| A computational/experimental assessment of antitumor activity of polymer nanoassemblies for ph-controlled drug delivery to primary and metastatic tumors LT Curtis, P Rychahou, Y Bae, HB Frieboes Pharmaceutical research 33 (10), 2552-2564, 2016 | 20 | 2016 |
| Pharmacokinetic/pharmacodynamic modeling of combination-chemotherapy for lung cancer LT Curtis, VH van Berkel, HB Frieboes Journal of theoretical biology 448, 38-52, 2018 | 16 | 2018 |
| Pancreatic adenocarcinoma response to chemotherapy enhanced with non-invasive radio frequency evaluated via an integrated experimental/computational approach MJ Ware, LT Curtis, M Wu, JC Ho, SJ Corr, SA Curley, B Godin, ... Scientific reports 7 (1), 1-13, 2017 | 15 | 2017 |
| Simulation of the protein-shedding kinetics of a fully vascularized tumor HB Frieboes, LT Curtis, M Wu, K Kani, P Mallick Cancer informatics 14, CIN. S35374, 2015 | 12 | 2015 |
| Development of halofluorochromic polymer nanoassemblies for the potential detection of liver metastatic colorectal cancer tumors using experimental and computational approaches D Reichel, LT Curtis, E Ehlman, BM Evers, P Rychahou, HB Frieboes, ... Pharmaceutical research 34 (11), 2385-2402, 2017 | 10 | 2017 |
| Modeling of Combination Chemotherapy and Immunotherapy for Lung Cancer LT Curtis, HB Frieboes 2019 41st Annual International Conference of the IEEE Engineering in …, 2019 | 9 | 2019 |
| Modeling of the tumor microenvironment to highlight nonlinear interactions between chemotherapeutic response and macrophage polarization state. LT Curtis, F Leonard, B Godin, HB Frieboes Journal of Clinical Oncology 36 (15_suppl), e24120-e24120, 2018 | 1 | 2018 |
| Intraperitoneal chemotherapy medical devices, kits, and methods C Gemborys, SL Pendleton, J Deis, J Haines, N Steinbrunner, L Curtis US Patent 10,335,573, 2019 | | 2019 |
| Abstract B39: Computational modeling of therapy using nanovectors altering macrophage subtypes to treat hypo-perfused tumor lesions F Leonard, LT Curtis, E Nassar, X Liu, M Ferrari, K Yokoi, B Godin, ... Cancer Research 77 (2 Supplement), B39-B39, 2017 | | 2017 |
| Computational modeling of therapy using nanovectors altering macrophage subtypes to treat hypoperfused tumor lesions F Leonard, LT Curtis, E Nassar, X Liu, M Ferrari, K Yokoi, B Godin, ... CANCER RESEARCH 77, 2017 | | 2017 |
