Cyclical DNA methylation of a transcriptionally active promoter R Métivier, R Gallais, C Tiffoche, C Le Péron, RZ Jurkowska, ... Nature 452 (7183), 45-50, 2008 | 1102 | 2008 |
Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation D Jia, RZ Jurkowska, X Zhang, A Jeltsch, X Cheng Nature 449 (7159), 248-251, 2007 | 1026 | 2007 |
Structure and function of mammalian DNA methyltransferases RZ Jurkowska, TP Jurkowski, A Jeltsch Chembiochem 12 (2), 206-222, 2011 | 893 | 2011 |
The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation A Dhayalan, A Rajavelu, P Rathert, R Tamas, RZ Jurkowska, S Ragozin, ... Journal of Biological Chemistry 285 (34), 26114-26120, 2010 | 640 | 2010 |
New concepts in DNA methylation A Jeltsch, RZ Jurkowska Trends in biochemical sciences 39 (7), 310-318, 2014 | 510 | 2014 |
Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail Y Zhang, R Jurkowska, S Soeroes, A Rajavelu, A Dhayalan, I Bock, ... Nucleic acids research 38 (13), 4246-4253, 2010 | 478 | 2010 |
Protein lysine methyltransferase G9a acts on non-histone targets P Rathert, A Dhayalan, M Murakami, X Zhang, R Tamas, R Jurkowska, ... Nature chemical biology 4 (6), 344-346, 2008 | 411 | 2008 |
Efficient targeted DNA methylation with chimeric dCas9–Dnmt3a–Dnmt3L methyltransferase P Stepper, G Kungulovski, RZ Jurkowska, T Chandra, F Krueger, ... Nucleic acids research 45 (4), 1703-1713, 2017 | 328 | 2017 |
Allosteric control of mammalian DNA methyltransferases–a new regulatory paradigm A Jeltsch, RZ Jurkowska Nucleic acids research 44 (18), 8556-8575, 2016 | 226 | 2016 |
Targeted methylation and gene silencing of VEGF-A in human cells by using a designed Dnmt3a–Dnmt3L single-chain fusion protein with increased DNA methylation activity AN Siddique, S Nunna, A Rajavelu, Y Zhang, RZ Jurkowska, R Reinhardt, ... Journal of molecular biology 425 (3), 479-491, 2013 | 199 | 2013 |
Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms L Gao, M Emperle, Y Guo, SA Grimm, W Ren, S Adam, H Uryu, ZM Zhang, ... Nature communications 11 (1), 3355, 2020 | 160 | 2020 |
Formation of nucleoprotein filaments by mammalian DNA methyltransferase Dnmt3a in complex with regulator Dnmt3L RZ Jurkowska, N Anspach, C Urbanke, D Jia, R Reinhardt, W Nellen, ... Nucleic acids research 36 (21), 6656-6663, 2008 | 148 | 2008 |
The UHRF1 protein stimulates the activity and specificity of the maintenance DNA methyltransferase DNMT1 by an allosteric mechanism P Bashtrykov, G Jankevicius, RZ Jurkowska, S Ragozin, A Jeltsch Journal of Biological Chemistry 289 (7), 4106-4115, 2014 | 138 | 2014 |
Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine C Champion, D Guianvarc'h, C Sénamaud-Beaufort, RZ Jurkowska, ... PloS one 5 (8), e12388, 2010 | 132 | 2010 |
Oligomerization and binding of the Dnmt3a DNA methyltransferase to parallel DNA molecules: heterochromatic localization and role of Dnmt3L RZ Jurkowska, A Rajavelu, N Anspach, C Urbanke, G Jankevicius, ... Journal of Biological Chemistry 286 (27), 24200-24207, 2011 | 128 | 2011 |
Mutational analysis of the catalytic domain of the murine Dnmt3a DNA-(cytosine C5)-methyltransferase H Gowher, P Loutchanwoot, O Vorobjeva, V Handa, RZ Jurkowska, ... Journal of molecular biology 357 (3), 928-941, 2006 | 125 | 2006 |
Specificity of Dnmt1 for methylation of hemimethylated CpG sites resides in its catalytic domain P Bashtrykov, G Jankevicius, A Smarandache, RZ Jurkowska, S Ragozin, ... Chemistry & biology 19 (5), 572-578, 2012 | 121 | 2012 |
C5‐DNA methyltransferase inhibitors: from screening to effects on zebrafish embryo development A Ceccaldi, A Rajavelu, C Champion, C Rampon, R Jurkowska, ... Chembiochem 12 (9), 1337-1345, 2011 | 92 | 2011 |
H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1 RZ Jurkowska, S Qin, G Kungulovski, W Tempel, Y Liu, P Bashtrykov, ... Nature communications 8 (1), 2057, 2017 | 82 | 2017 |
Rapid synthesis of new DNMT inhibitors derivatives of procainamide L Halby, C Champion, C Sénamaud‐Beaufort, S Ajjan, T Drujon, ... Chembiochem 13 (1), 157-165, 2012 | 75 | 2012 |