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Renata Jurkowska
Renata Jurkowska
Cardiff University, School of Biosciences
Bestätigte E-Mail-Adresse bei cardiff.ac.uk - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Cyclical DNA methylation of a transcriptionally active promoter
R Métivier, R Gallais, C Tiffoche, C Le Péron, RZ Jurkowska, ...
Nature 452 (7183), 45-50, 2008
10792008
Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation
D Jia, RZ Jurkowska, X Zhang, A Jeltsch, X Cheng
Nature 449 (7159), 248-251, 2007
9742007
Structure and function of mammalian DNA methyltransferases
RZ Jurkowska, TP Jurkowski, A Jeltsch
Chembiochem 12 (2), 206-222, 2011
8502011
The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation
A Dhayalan, A Rajavelu, P Rathert, R Tamas, RZ Jurkowska, S Ragozin, ...
Journal of Biological Chemistry 285 (34), 26114-26120, 2010
6052010
New concepts in DNA methylation
A Jeltsch, RZ Jurkowska
Trends in biochemical sciences 39 (7), 310-318, 2014
4832014
Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail
Y Zhang, R Jurkowska, S Soeroes, A Rajavelu, A Dhayalan, I Bock, ...
Nucleic acids research 38 (13), 4246-4253, 2010
4442010
Protein lysine methyltransferase G9a acts on non-histone targets
P Rathert, A Dhayalan, M Murakami, X Zhang, R Tamas, R Jurkowska, ...
Nature chemical biology 4 (6), 344-346, 2008
3952008
Efficient targeted DNA methylation with chimeric dCas9–Dnmt3a–Dnmt3L methyltransferase
P Stepper, G Kungulovski, RZ Jurkowska, T Chandra, F Krueger, ...
Nucleic acids research 45 (4), 1703-1713, 2017
2822017
Allosteric control of mammalian DNA methyltransferases–a new regulatory paradigm
A Jeltsch, RZ Jurkowska
Nucleic acids research 44 (18), 8556-8575, 2016
2012016
Targeted methylation and gene silencing of VEGF-A in human cells by using a designed Dnmt3a–Dnmt3L single-chain fusion protein with increased DNA methylation activity
AN Siddique, S Nunna, A Rajavelu, Y Zhang, RZ Jurkowska, R Reinhardt, ...
Journal of molecular biology 425 (3), 479-491, 2013
1852013
Formation of nucleoprotein filaments by mammalian DNA methyltransferase Dnmt3a in complex with regulator Dnmt3L
RZ Jurkowska, N Anspach, C Urbanke, D Jia, R Reinhardt, W Nellen, ...
Nucleic acids research 36 (21), 6656-6663, 2008
1352008
The UHRF1 protein stimulates the activity and specificity of the maintenance DNA methyltransferase DNMT1 by an allosteric mechanism
P Bashtrykov, G Jankevicius, RZ Jurkowska, S Ragozin, A Jeltsch
Journal of Biological Chemistry 289 (7), 4106-4115, 2014
1332014
Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine
C Champion, D Guianvarc'h, C Sénamaud-Beaufort, RZ Jurkowska, ...
PloS one 5 (8), e12388, 2010
1282010
Mutational analysis of the catalytic domain of the murine Dnmt3a DNA-(cytosine C5)-methyltransferase
H Gowher, P Loutchanwoot, O Vorobjeva, V Handa, RZ Jurkowska, ...
Journal of molecular biology 357 (3), 928-941, 2006
1192006
Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms
L Gao, M Emperle, Y Guo, SA Grimm, W Ren, S Adam, H Uryu, ZM Zhang, ...
Nature communications 11 (1), 3355, 2020
1172020
Oligomerization and binding of the Dnmt3a DNA methyltransferase to parallel DNA molecules: heterochromatic localization and role of Dnmt3L
RZ Jurkowska, A Rajavelu, N Anspach, C Urbanke, G Jankevicius, ...
Journal of Biological Chemistry 286 (27), 24200-24207, 2011
1162011
Specificity of Dnmt1 for methylation of hemimethylated CpG sites resides in its catalytic domain
P Bashtrykov, G Jankevicius, A Smarandache, RZ Jurkowska, S Ragozin, ...
Chemistry & biology 19 (5), 572-578, 2012
1102012
C5‐DNA methyltransferase inhibitors: from screening to effects on zebrafish embryo development
A Ceccaldi, A Rajavelu, C Champion, C Rampon, R Jurkowska, ...
Chembiochem 12 (9), 1337-1345, 2011
902011
Rapid synthesis of new DNMT inhibitors derivatives of procainamide
L Halby, C Champion, C Sénamaud‐Beaufort, S Ajjan, T Drujon, ...
Chembiochem 13 (1), 157-165, 2012
722012
H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1
RZ Jurkowska, S Qin, G Kungulovski, W Tempel, Y Liu, P Bashtrykov, ...
Nature communications 8 (1), 2057, 2017
692017
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