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Guangxu Jin
Guangxu Jin
Assistant Professor, Cancer Biology, Wake Forest University Comprehensive Cancer Center
Bestätigte E-Mail-Adresse bei wakehealth.edu
Titel
Zitiert von
Zitiert von
Jahr
Toward better drug repositioning: prioritizing and integrating existing methods into efficient pipelines
G Jin, STC Wong
Drug discovery today 19 (5), 637-644, 2014
4682014
Loss of XIST in breast cancer activates MSN-c-Met and reprograms microglia via exosomal miRNA to promote brain metastasis
F Xing, Y Liu, SY Wu, K Wu, S Sharma, YY Mo, J Feng, S Sanders, G Jin, ...
Cancer research 78 (15), 4316-4330, 2018
2822018
Tumor mutational burden is a determinant of immune-mediated survival in breast cancer
A Thomas, ED Routh, A Pullikuth, G Jin, J Su, JW Chou, KA Hoadley, ...
Oncoimmunology 7 (10), e1490854, 2018
2112018
Safety and tolerability of the first-in-class agent CPI-613 in combination with modified FOLFIRINOX in patients with metastatic pancreatic cancer: a single-centre, open-label …
A Alistar, BB Morris, R Desnoyer, HD Klepin, K Hosseinzadeh, C Clark, ...
The lancet oncology 18 (6), 770-778, 2017
2102017
Discovering functions and revealing mechanisms at molecular level from biological networks
S Zhang, G Jin, XS Zhang, L Chen
Proteomics 7 (16), 2856-2869, 2007
1432007
Dissecting intratumoral myeloid cell plasticity by single cell RNA‐seq
Q Song, GA Hawkins, L Wudel, PC Chou, E Forbes, AK Pullikuth, L Liu, ...
Cancer medicine 8 (6), 3072-3085, 2019
1322019
Chloroquine eliminates cancer stem cells through deregulation of Jak2 and DNMT1
DS Choi, E Blanco, YS Kim, AA Rodriguez, H Zhao, THM Huang, ...
Stem cells 32 (9), 2309-2323, 2014
1302014
A novel method of transcriptional response analysis to facilitate drug repositioning for cancer therapy
G Jin, C Fu, H Zhao, K Cui, J Chang, STC Wong
Cancer research 72 (1), 33-44, 2012
1082012
Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative breast cancers and HER2-enriched breast cancer
KWHWL Sherona R. Sirkisoon, Richard L. Carpenter, Tadas Rimkus, Ashley ...
Oncogene, 2018
1072018
IL-4 together with IL-1β induces antitumor Th9 cell differentiation in the absence of TGF-β signaling
G Xue, G Jin, J Fang, Y Lu
Nature communications 10 (1), 1376, 2019
1022019
Modeling the relationship of epigenetic modifications to transcription factor binding
L Liu, G Jin, X Zhou
Nucleic acids research 43 (8), 3873-3885, 2015
1012015
A phase I study of CPI-613 in combination with high-dose cytarabine and mitoxantrone for relapsed or refractory acute myeloid leukemia
TS Pardee, RG Anderson, KM Pladna, S Isom, LP Ghiraldeli, LD Miller, ...
Clinical Cancer Research 24 (9), 2060-2073, 2018
932018
The knowledge-integrated network biomarkers discovery for major adverse cardiac events
G Jin, X Zhou, H Wang, H Zhao, K Cui, XS Zhang, L Chen, SL Hazen, K Li, ...
Journal of proteome research 7 (9), 4013-4021, 2008
772008
Hubs with network motifs organize modularity dynamically in the protein-protein interaction network of yeast
G Jin, S Zhang, XS Zhang, L Chen
PloS one 2 (11), e1207, 2007
762007
An enhanced Petri-net model to predict synergistic effects of pairwise drug combinations from gene microarray data
G Jin, H Zhao, X Zhou, STC Wong
Bioinformatics 27 (13), i310-i316, 2011
642011
Novel modeling of cancer cell signaling pathways enables systematic drug repositioning for distinct breast cancer metastases
H Zhao, G Jin, K Cui, D Ren, T Liu, P Chen, S Wong, F Li, Y Fan, ...
Cancer research 73 (20), 6149-6163, 2013
562013
Transcriptional signaling pathways inversely regulated in Alzheimer's disease and glioblastoma multiform
T Liu, D Ren, X Zhu, Z Yin, G Jin, Z Zhao, D Robinson, X Li, K Wong, ...
Scientific reports 3 (1), 3467, 2013
502013
The effect of mTOR inhibition alone or combined with MEK inhibitors on brain metastasis: an in vivo analysis in triple-negative breast cancer models
H Zhao, K Cui, F Nie, L Wang, MB Brandl, G Jin, F Li, Y Mao, Z Xue, ...
Breast cancer research and treatment 131, 425-436, 2012
502012
Chapter 17: bioimage informatics for systems pharmacology
F Li, Z Yin, G Jin, H Zhao, STC Wong
PLoS Computational Biology 9 (4), e1003043, 2013
442013
Tumour-specific amplitude-modulated radiofrequency electromagnetic fields induce differentiation of hepatocellular carcinoma via targeting Cav3. 2 T-type voltage-gated calcium …
H Jimenez, M Wang, JW Zimmerman, MJ Pennison, S Sharma, T Surratt, ...
EBioMedicine 44, 209-224, 2019
402019
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