Toward better drug repositioning: prioritizing and integrating existing methods into efficient pipelines G Jin, STC Wong Drug discovery today 19 (5), 637-644, 2014 | 468 | 2014 |
Loss of XIST in breast cancer activates MSN-c-Met and reprograms microglia via exosomal miRNA to promote brain metastasis F Xing, Y Liu, SY Wu, K Wu, S Sharma, YY Mo, J Feng, S Sanders, G Jin, ... Cancer research 78 (15), 4316-4330, 2018 | 282 | 2018 |
Tumor mutational burden is a determinant of immune-mediated survival in breast cancer A Thomas, ED Routh, A Pullikuth, G Jin, J Su, JW Chou, KA Hoadley, ... Oncoimmunology 7 (10), e1490854, 2018 | 211 | 2018 |
Safety and tolerability of the first-in-class agent CPI-613 in combination with modified FOLFIRINOX in patients with metastatic pancreatic cancer: a single-centre, open-label … A Alistar, BB Morris, R Desnoyer, HD Klepin, K Hosseinzadeh, C Clark, ... The lancet oncology 18 (6), 770-778, 2017 | 210 | 2017 |
Discovering functions and revealing mechanisms at molecular level from biological networks S Zhang, G Jin, XS Zhang, L Chen Proteomics 7 (16), 2856-2869, 2007 | 143 | 2007 |
Dissecting intratumoral myeloid cell plasticity by single cell RNA‐seq Q Song, GA Hawkins, L Wudel, PC Chou, E Forbes, AK Pullikuth, L Liu, ... Cancer medicine 8 (6), 3072-3085, 2019 | 132 | 2019 |
Chloroquine eliminates cancer stem cells through deregulation of Jak2 and DNMT1 DS Choi, E Blanco, YS Kim, AA Rodriguez, H Zhao, THM Huang, ... Stem cells 32 (9), 2309-2323, 2014 | 130 | 2014 |
A novel method of transcriptional response analysis to facilitate drug repositioning for cancer therapy G Jin, C Fu, H Zhao, K Cui, J Chang, STC Wong Cancer research 72 (1), 33-44, 2012 | 108 | 2012 |
Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative breast cancers and HER2-enriched breast cancer KWHWL Sherona R. Sirkisoon, Richard L. Carpenter, Tadas Rimkus, Ashley ... Oncogene, 2018 | 107 | 2018 |
IL-4 together with IL-1β induces antitumor Th9 cell differentiation in the absence of TGF-β signaling G Xue, G Jin, J Fang, Y Lu Nature communications 10 (1), 1376, 2019 | 102 | 2019 |
Modeling the relationship of epigenetic modifications to transcription factor binding L Liu, G Jin, X Zhou Nucleic acids research 43 (8), 3873-3885, 2015 | 101 | 2015 |
A phase I study of CPI-613 in combination with high-dose cytarabine and mitoxantrone for relapsed or refractory acute myeloid leukemia TS Pardee, RG Anderson, KM Pladna, S Isom, LP Ghiraldeli, LD Miller, ... Clinical Cancer Research 24 (9), 2060-2073, 2018 | 93 | 2018 |
The knowledge-integrated network biomarkers discovery for major adverse cardiac events G Jin, X Zhou, H Wang, H Zhao, K Cui, XS Zhang, L Chen, SL Hazen, K Li, ... Journal of proteome research 7 (9), 4013-4021, 2008 | 77 | 2008 |
Hubs with network motifs organize modularity dynamically in the protein-protein interaction network of yeast G Jin, S Zhang, XS Zhang, L Chen PloS one 2 (11), e1207, 2007 | 76 | 2007 |
An enhanced Petri-net model to predict synergistic effects of pairwise drug combinations from gene microarray data G Jin, H Zhao, X Zhou, STC Wong Bioinformatics 27 (13), i310-i316, 2011 | 64 | 2011 |
Novel modeling of cancer cell signaling pathways enables systematic drug repositioning for distinct breast cancer metastases H Zhao, G Jin, K Cui, D Ren, T Liu, P Chen, S Wong, F Li, Y Fan, ... Cancer research 73 (20), 6149-6163, 2013 | 56 | 2013 |
Transcriptional signaling pathways inversely regulated in Alzheimer's disease and glioblastoma multiform T Liu, D Ren, X Zhu, Z Yin, G Jin, Z Zhao, D Robinson, X Li, K Wong, ... Scientific reports 3 (1), 3467, 2013 | 50 | 2013 |
The effect of mTOR inhibition alone or combined with MEK inhibitors on brain metastasis: an in vivo analysis in triple-negative breast cancer models H Zhao, K Cui, F Nie, L Wang, MB Brandl, G Jin, F Li, Y Mao, Z Xue, ... Breast cancer research and treatment 131, 425-436, 2012 | 50 | 2012 |
Chapter 17: bioimage informatics for systems pharmacology F Li, Z Yin, G Jin, H Zhao, STC Wong PLoS Computational Biology 9 (4), e1003043, 2013 | 44 | 2013 |
Tumour-specific amplitude-modulated radiofrequency electromagnetic fields induce differentiation of hepatocellular carcinoma via targeting Cav3. 2 T-type voltage-gated calcium … H Jimenez, M Wang, JW Zimmerman, MJ Pennison, S Sharma, T Surratt, ... EBioMedicine 44, 209-224, 2019 | 40 | 2019 |