Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia P Ntziachristos, A Tsirigos, PV Vlierberghe, J Nedjic, T Trimarchi, ... Nature medicine 18 (2), 298-302, 2012 | 617 | 2012 |
Genome-wide mapping and characterization of Notch-regulated long noncoding RNAs in acute leukemia T Trimarchi, E Bilal, P Ntziachristos, G Fabbri, R Dalla-Favera, A Tsirigos, ... Cell 158 (3), 593-606, 2014 | 482 | 2014 |
From fly wings to targeted cancer therapies: a centennial for notch signaling P Ntziachristos, JS Lim, J Sage, I Aifantis Cancer cell 25 (3), 318-334, 2014 | 440 | 2014 |
Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia P Ntziachristos, A Tsirigos, GG Welstead, T Trimarchi, S Bakogianni, L Xu, ... Nature 514 (7523), 513-517, 2014 | 398 | 2014 |
The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability B King, T Trimarchi, L Reavie, L Xu, J Mullenders, P Ntziachristos, ... Cell 153 (7), 1552-1566, 2013 | 366 | 2013 |
Deregulation of DUX4 and ERG in acute lymphoblastic leukemia J Zhang, K McCastlain, H Yoshihara, B Xu, Y Chang, ML Churchman, ... Nature genetics 48 (12), 1481-1489, 2016 | 328 | 2016 |
Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes R Di Micco, B Fontanals-Cirera, V Low, P Ntziachristos, SK Yuen, ... Cell reports 9 (1), 234-247, 2014 | 251 | 2014 |
Notch pathway activation targets AML-initiating cell homeostasis and differentiation C Lobry, P Ntziachristos, D Ndiaye-Lobry, P Oh, L Cimmino, N Zhu, ... Journal of Experimental Medicine 210 (2), 301-319, 2013 | 193 | 2013 |
Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia A Kloetgen, P Thandapani, P Ntziachristos, Y Ghebrechristos, S Nomikou, ... Nature genetics 52 (4), 388-400, 2020 | 192 | 2020 |
Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy L Wang, Z Zhao, PA Ozark, D Fantini, SA Marshall, EJ Rendleman, ... Nature medicine 24 (6), 758-769, 2018 | 167 | 2018 |
Stratification of TAD boundaries reveals preferential insulation of super-enhancers by strong boundaries Y Gong, C Lazaris, T Sakellaropoulos, A Lozano, P Kambadur, ... Nature communications 9 (1), 542, 2018 | 155 | 2018 |
Cardiac Myocyte KLF5 Regulates Ppara Expression and Cardiac Function K Drosatos, NM Pollak, CJ Pol, P Ntziachristos, F Willecke, MC Valenti, ... Circulation research 118 (2), 241-253, 2016 | 123 | 2016 |
Histone demethylases in physiology and cancer: a tale of two enzymes, JMJD3 and UTX KM Arcipowski, CA Martinez, P Ntziachristos Current opinion in genetics & development 36, 59-67, 2016 | 99 | 2016 |
Emerging concepts of epigenetic dysregulation in hematological malignancies P Ntziachristos, O Abdel-Wahab, I Aifantis Nature immunology 17 (9), 1016-1024, 2016 | 97 | 2016 |
Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation C Fang, Z Wang, C Han, SL Safgren, KA Helmin, ER Adelman, V Serafin, ... Genome biology 21, 1-30, 2020 | 96 | 2020 |
USP7 cooperates with NOTCH1 to drive the oncogenic transcriptional program in T-cell leukemia Q Jin, CA Martinez, KM Arcipowski, Y Zhu, BT Gutierrez-Diaz, KK Wang, ... Clinical Cancer Research 25 (1), 222-239, 2019 | 92 | 2019 |
HiC-bench: comprehensive and reproducible Hi-C data analysis designed for parameter exploration and benchmarking C Lazaris, S Kelly, P Ntziachristos, I Aifantis, A Tsirigos BMC genomics 18, 1-16, 2017 | 85 | 2017 |
Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a A Strikoudis, C Lazaris, T Trimarchi, AL Galvao Neto, Y Yang, ... Nature cell biology 18 (11), 1127-1138, 2016 | 76 | 2016 |
Posttranslational regulation of FOXA1 by Polycomb and BUB3/USP7 deubiquitin complex in prostate cancer SH Park, K Fong, J Kim, F Wang, X Lu, Y Lee, LT Brea, K Wadosky, C Guo, ... Science advances 7 (15), eabe2261, 2021 | 61 | 2021 |
Posttranslational regulation of the exon skipping machinery controls aberrant splicing in leukemia Y Zhou, C Han, E Wang, AH Lorch, V Serafin, BK Cho, BT Gutierrez Diaz, ... Cancer discovery 10 (9), 1388-1409, 2020 | 52 | 2020 |